-
Je něco špatně v tomto záznamu ?
ADHD symptoms induced by prenatal methamphetamine exposure
A. Ochozková, L. Mihalčíková, A. Yamamotová, R. Šlamberová
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články
NLK
Directory of Open Access Journals
od 1991
Free Medical Journals
od 1998
ProQuest Central
od 2005-01-01
Medline Complete (EBSCOhost)
od 2006-01-01
Nursing & Allied Health Database (ProQuest)
od 2005-01-01
Health & Medicine (ProQuest)
od 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
od 1998
- MeSH
- hyperkinetická porucha chemicky indukované MeSH
- hyperkineze chemicky indukované MeSH
- methamfetamin škodlivé účinky MeSH
- potkani Wistar MeSH
- stimulanty centrálního nervového systému škodlivé účinky MeSH
- těhotenství MeSH
- zpožděný efekt prenatální expozice * MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
Methamphetamine is commonly used psychostimulant in the Czech Republic and is often abused by pregnant women. Methamphetamine may cause abnormalities in placenta and umbilical cord that results in hypoxia and malnutrition. ADHD is a mental disorder with a heterogeneous origin. The number of patients suffering from ADHD is growing. The pathophysiological mechanisms causing ADHD have not yet been clarified. There are very few rat models for ADHD and include genetic models, chemically induced models (ethanol, nicotine, PCBs, 6-hydroxydopamine lesion) or environmentally induced models (anoxia). The aim of the present study was to test prenatal methamphetamine exposure (5 mg/kg) as a potential novel animal model for ADHD. We found that adult male offspring prenatally exposed to methamphetamine presented hyperactivity while exploring novel environments. Together with cognition changes found in our previous studies, these might represent symptoms similar to those seen in ADHD. More experiments are planned to investigate our hypothesis.
Citace poskytuje Crossref.org
Literatura
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21028181
- 003
- CZ-PrNML
- 005
- 20220328170624.0
- 007
- ta
- 008
- 211105s2019 xr d f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.33549/physiolres.934358 $2 doi
- 035 __
- $a (PubMed)31928052
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Ochozková, Anna $7 xx0233223 $u Department of Physiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic
- 245 10
- $a ADHD symptoms induced by prenatal methamphetamine exposure / $c A. Ochozková, L. Mihalčíková, A. Yamamotová, R. Šlamberová
- 504 __
- $a Literatura
- 520 9_
- $a Methamphetamine is commonly used psychostimulant in the Czech Republic and is often abused by pregnant women. Methamphetamine may cause abnormalities in placenta and umbilical cord that results in hypoxia and malnutrition. ADHD is a mental disorder with a heterogeneous origin. The number of patients suffering from ADHD is growing. The pathophysiological mechanisms causing ADHD have not yet been clarified. There are very few rat models for ADHD and include genetic models, chemically induced models (ethanol, nicotine, PCBs, 6-hydroxydopamine lesion) or environmentally induced models (anoxia). The aim of the present study was to test prenatal methamphetamine exposure (5 mg/kg) as a potential novel animal model for ADHD. We found that adult male offspring prenatally exposed to methamphetamine presented hyperactivity while exploring novel environments. Together with cognition changes found in our previous studies, these might represent symptoms similar to those seen in ADHD. More experiments are planned to investigate our hypothesis.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a hyperkinetická porucha $x chemicky indukované $7 D001289
- 650 _2
- $a stimulanty centrálního nervového systému $x škodlivé účinky $7 D000697
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a hyperkineze $x chemicky indukované $7 D006948
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a methamfetamin $x škodlivé účinky $7 D008694
- 650 _2
- $a těhotenství $7 D011247
- 650 12
- $a zpožděný efekt prenatální expozice $7 D011297
- 650 _2
- $a potkani Wistar $7 D017208
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Mihalčíková, Lýdia $7 xx0233220 $u Department of Physiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic
- 700 1_
- $a Yamamotová, Anna, $d 1953- $7 xx0060358 $u Department of Physiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic
- 700 1_
- $a Šlamberová, Romana $7 xx0052834 $u Department of Physiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic
- 773 0_
- $w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 68, Suppl 3 (2019), s. S347-S352
- 773 0_
- $t Proceedings of the ... Physiological days $g (2019), s. S347-S352 $w MED00183838
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/31928052 $y Pubmed
- 910 __
- $a ABA008 $b A 4120 $c 266 $y p $z 0
- 990 __
- $a 20211105 $b ABA008
- 991 __
- $a 20220328170622 $b ABA008
- 999 __
- $a ok $b bmc $g 1735502 $s 1148726
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2019 $b 68 $c Suppl 3 $d S347-S352 $e 20191220 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
- BMC __
- $a 2019 $d S347-S352 $m Proceedings of the ... Physiological days $x MED00183838
- LZP __
- $b NLK118 $a Pubmed-20211105
