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Electrospun nanofibers as support for the healing of intestinal anastomoses
M. Kralovic, M. Vjaclovsky, A. Kestlerova, F. Rustichelli, J. Hoch, E. Amler
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články, přehledy
Grantová podpora
NV16-29680A
MZ0
CEP - Centrální evidence projektů
Digitální knihovna NLK
Plný text - Článek
NLK
Directory of Open Access Journals
od 1991
Free Medical Journals
od 1998
ProQuest Central
od 2005-01-01
Medline Complete (EBSCOhost)
od 2006-01-01
Nursing & Allied Health Database (ProQuest)
od 2005-01-01
Health & Medicine (ProQuest)
od 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
od 1998
- MeSH
- anastomóza chirurgická * MeSH
- biokompatibilní materiály MeSH
- lidé MeSH
- nanovlákna terapeutické užití MeSH
- netěsnost anastomózy prevence a kontrola MeSH
- regenerace * MeSH
- střeva chirurgie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
The breakdown of intestinal anastomosis is a serious postsurgical complication. The worst complication is anastomotic leakage, resulting in contaminated peritoneal cavity, sepsis, multi-organ failure and even death. In problematic locations like the rectum, the leakage rate has not yet fallen below 10 %. Such a life-threatening condition is the result of impaired healing in the anastomotic wound. It is still vital to find innovative strategies and techniques in order to support regeneration of the anastomotic wound. This paper reviews the surgical techniques and biomaterials used, tested or published. Electrospun nanofibers are introduced as a novel and potential material in gastrointestinal surgery. Nanofibers possess several, unique, physical and chemical properties, that may effectively stimulate cell proliferation and collagen production; a key requirement for the healed intestinal wound.
2nd Medical Faculty Charles University Prague Prague Czech Republic
Citace poskytuje Crossref.org
Literatura
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