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Processing of emotionally ambiguous stimuli in eating disorders: an fMRI pilot study
P. Holštajn Zemánková, M. Gajdoš, M. Světlák, M. Bareš, J. Širůček, T. Kašpárek
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články
Grantová podpora
65269705
Ministerstvo Zdravotnictví Ceské Republiky
GA15-20970S
Grantová Agentura České Republiky
LM2018129Czech-BioImaging
Ministerstvo Školství, Mládeže a Tělovýchovy
NLK
ProQuest Central
od 1997-03-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 1997-03-01 do Před 1 rokem
- MeSH
- afektivní symptomy MeSH
- emoce MeSH
- lidé MeSH
- magnetická rezonanční tomografie * MeSH
- pilotní projekty MeSH
- poruchy příjmu potravy * diagnostické zobrazování MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
PURPOSE: People with eating disorders (EDs) have difficulties understanding their own emotions and recognizing the emotions of others, especially in ambiguous settings. We examined the neuronal mechanisms underlying the emotion processing of ambiguous interpersonal stimuli in EDs and healthy controls (HCs). METHODS: The fMRI data were acquired by a blocked experimental design with 28 women (14 EDs) during the visual presentation of a modified Thematic Apperception Test. RESULTS: EDs showed very strong associations between experienced and inferred emotions evoked by the stimuli; no such relationship was found in HCs. HCs displayed elevated left anterior insula activity during the mentalizing condition; EDs showed increased activity in the right supramarginal gyrus and medial prefrontal cortex. CONCLUSION: The two groups seem to apply different strategies for judging emotionally ambiguous stimuli, albeit resulting in equivalent judgments. We assume that activity in the supramarginal gyrus and insula in EDs is linked with suppressing their own perspective while considering emotional states, probably due to alexithymia and the lack of awareness of their own mental states. We hypothesize that the strong correlation between experienced and inferred emotions in EDs could reflect their tendency to use others as a reference point for perceiving themselves and gaining information about their affective state. LEVEL OF EVIDENCE: No level of evidence, this is a basic science study.
Behavioral and Social Neuroscience CEITEC Masaryk University Brno Czech Republic
Department of Psychiatry Masaryk University and University Hospital Brno Brno Czech Republic
Department of Psychology Faculty of Social Studies Masaryk University Brno Czech Republic
Multimodal and Functional Imaging Laboratory CEITEC Masaryk University Brno Czech Republic
Citace poskytuje Crossref.org
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- $a Holštajn Zemánková, Petra $u First Department of Neurology, St. Anne's University Hospital and School of Medicine, Masaryk University, Brno, Czech Republic. petra.zemankova@mail.muni.cz $u Behavioral and Social Neuroscience, CEITEC, Masaryk University, Brno, Czech Republic. petra.zemankova@mail.muni.cz $7 xx0268813
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- $a PURPOSE: People with eating disorders (EDs) have difficulties understanding their own emotions and recognizing the emotions of others, especially in ambiguous settings. We examined the neuronal mechanisms underlying the emotion processing of ambiguous interpersonal stimuli in EDs and healthy controls (HCs). METHODS: The fMRI data were acquired by a blocked experimental design with 28 women (14 EDs) during the visual presentation of a modified Thematic Apperception Test. RESULTS: EDs showed very strong associations between experienced and inferred emotions evoked by the stimuli; no such relationship was found in HCs. HCs displayed elevated left anterior insula activity during the mentalizing condition; EDs showed increased activity in the right supramarginal gyrus and medial prefrontal cortex. CONCLUSION: The two groups seem to apply different strategies for judging emotionally ambiguous stimuli, albeit resulting in equivalent judgments. We assume that activity in the supramarginal gyrus and insula in EDs is linked with suppressing their own perspective while considering emotional states, probably due to alexithymia and the lack of awareness of their own mental states. We hypothesize that the strong correlation between experienced and inferred emotions in EDs could reflect their tendency to use others as a reference point for perceiving themselves and gaining information about their affective state. LEVEL OF EVIDENCE: No level of evidence, this is a basic science study.
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