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Factors relating to mortality in septic patients in Vietnamese intensive care units from a subgroup analysis of MOSAICS II study

SN. Do, CQ. Luong, DT. Pham, MH. Nguyen, NT. Nguyen, DQ. Huynh, QTA. Hoang, CX. Dao, TM. Le, HN. Bui, HT. Nguyen, HB. Hoang, TTP. Le, LTB. Nguyen, PT. Duong, TD. Nguyen, YH. Vu, GTT. Pham, T. Van Bui, TTN. Pham, HT. Hoang, C. Van Bui, NM. Nguyen,...

. 2021 ; 11 (1) : 18924. [pub] 20210923

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články, multicentrická studie, pozorovací studie

Perzistentní odkaz   https://www.medvik.cz/link/bmc22003684

Sepsis is the most common cause of in-hospital deaths, especially from low-income and lower-middle-income countries (LMICs). This study aimed to investigate the mortality rate and associated factors from sepsis in intensive care units (ICUs) in an LMIC. We did a multicenter cross-sectional study of septic patients presenting to 15 adult ICUs throughout Vietnam on the 4 days representing the different seasons of 2019. Of 252 patients, 40.1% died in hospital and 33.3% died in ICU. ICUs with accredited training programs (odds ratio, OR: 0.309; 95% confidence interval, CI 0.122-0.783) and completion of the 3-h sepsis bundle (OR: 0.294; 95% CI 0.083-1.048) were associated with decreased hospital mortality. ICUs with intensivist-to-patient ratio of 1:6 to 8 (OR: 4.533; 95% CI 1.621-12.677), mechanical ventilation (OR: 3.890; 95% CI 1.445-10.474) and renal replacement therapy (OR: 2.816; 95% CI 1.318-6.016) were associated with increased ICU mortality, in contrast to non-surgical source control (OR: 0.292; 95% CI 0.126-0.678) which was associated with decreased ICU mortality. Improvements are needed in the management of sepsis in Vietnam such as increasing resources in critical care settings, making accredited training programs more available, improving compliance with sepsis bundles of care, and treating underlying illness and shock optimally in septic patients.

Center for Emergency Medicine Bach Mai Hospital 78 Giai Phong road Phuong Mai ward Dong Da district Hanoi 100000 Vietnam

Department of Critical Care Emergency Medicine and Clinical Toxicology Faculty of Medicine Ho Chi Minh City University of Medicine and Pharmacy Ho Chi Minh City 700000 Vietnam

Department of Emergency and Critical Care Medicine Faculty of Medicine Hue University of Medicine and Pharmacy Hue City Thua Thien Hue 530000 Vietnam

Department of Emergency and Critical Care Medicine Hanoi Medical University Hanoi 100000 Vietnam

Department of Emergency Medicine Emory University School of Medicine Atlanta GA 30322 USA

Department of Health Organization and Management Faculty of Public Health Thai Binh University of Medicine and Pharmacy Thai Binh 410000 Vietnam

Department of Intensive Care and Poison Control Vietnam Czechoslovakia Friendship Hospital Hai Phong 180000 Vietnam

Department of Intensive Care Bach Mai Hospital Hanoi 100000 Vietnam

Department of Nutrition and Food Safety Faculty of Public Health Thai Binh University of Medicine and Pharmacy Thai Binh 410000 Vietnam

Division of Respiratory and Critical Care Medicine Department of Medicine National University Health System Singapore 119228 Singapore

Emergency and Critical Care Department Hanoi Medical University Hospital Hanoi Medical University Hanoi 100000 Vietnam

Emergency Department Hue Central General Hospital Hue City Thua Thien Hue 530000 Vietnam

Emergency Department Thanh Nhan General Hospital Hanoi 100000 Vietnam

Emory University Rollins School of Public Health Atlanta GA 30322 USA

Faculty of Medicine University of Medicine and Pharmacy Vietnam National University Hanoi 100000 Vietnam

FAST and Chronic Programmes Alexandra Hospital National University Health System Singapore 159964 Singapore

Intensive Care Department Cho Ray Hospital Ho Chi Minh City 700000 Vietnam

Intensive Care Unit 115 People's Hospital Ho Chi Minh City 700000 Vietnam

Intensive Care Unit Bai Chay General Hospital Quang Ninh 200000 Vietnam

Intensive Care Unit Can Tho Central General Hospital Can Tho 900000 Vietnam

Intensive Care Unit Da Nang Hospital Da Nang 550000 Vietnam

Intensive Care Unit Dong Da General Hospital Hanoi 100000 Vietnam

Intensive Care Unit Hue Central General Hospital Hue City Thua Thien Hue 530000 Vietnam

Intensive Care Unit Saint Paul General Hospital Hanoi 100000 Vietnam

Intensive Care Unit Thai Nguyen Central General Hospital Thai Nguyen 250000 Vietnam

Intensive Care Unit Vinmec Times City International Hospital Hanoi 100000 Vietnam

Citace poskytuje Crossref.org

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