-
Je něco špatně v tomto záznamu ?
Duration of Venoarterial Extracorporeal Membrane Oxygenation and Mortality in Postcardiotomy Cardiogenic Shock
G. Mariscalco, Z. El-Dean, H. Yusuff, T. Fux, AM. Dell'Aquila, K. Jónsson, S. Ragnarsson, A. Fiore, M. Dalén, D. di Perna, G. Gatti, T. Juvonen, S. Zipfel, A. Perrotti, K. Bounader, K. Alkhamees, A. Loforte, A. Lechiancole, M. Pol, C. Spadaccio,...
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, multicentrická studie
- MeSH
- centra terciární péče MeSH
- kardiogenní šok * mortalita terapie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mimotělní membránová oxygenace * MeSH
- mortalita v nemocnicích MeSH
- retrospektivní studie MeSH
- senioři MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
OBJECTIVE: The optimal duration of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in patients affected by postcardiotomy cardiogenic shock (PCS) remains controversial. The present study was conducted to investigate the effect of VA-ECMO duration on hospital outcomes. DESIGN: Retrospective analysis of an international registry. SETTING: Multicenter study including 19 tertiary university hospitals. PARTICIPANTS: Between January 2010 and March 2018, data on PCS patients receiving VA-ECMO were retrieved from the multicenter PC-ECMO registry. INTERVENTIONS: Patients were stratified according to the following different durations of VA-ECMO therapy: ≤three days, four-to-seven days, eight-to-ten days, and >ten days. MEASUREMENTS AND MAIN RESULTS: A total of 725 patients, with a mean age of 62.9 ± 12.9 years, were included. The mean duration of VA-ECMO was 7.1 ± 6.3 days (range 0-39 d), and 39.4% of patients were supported for ≤three days, 29.1% for four-seven days, 15.3% for eight-ten days, and finally 20.7% for >ten days. A total of 391 (53.9%) patients were weaned from VA-ECMO successfully; however, 134 (34.3%) of those patients died before discharge. Multivariate logistic regression showed that prolonged duration of VA-ECMO therapy (four-seven days: adjusted rate 53.6%, odds ratio [OR] 0.28, 95% confidence interval [CI] 0.18-0.44; eight-ten days: adjusted rate 61.3%, OR 0.51, 95% CI 0.29-0.87; and >ten days: adjusted rate 59.3%, OR 0.49, 95% CI 0.31-0.81) was associated with lower risk of mortality compared with VA-ECMO lasting ≤three days (adjusted rate 78.3%). Patients requiring VA-ECMO therapy for eight-ten days (OR 1.96, 95% CI 1.15-3.33) and >10 days (OR 1.85, 95% CI 1.14-3.02) had significantly greater mortality compared with those on VA-ECMO for 4 to 7 days. CONCLUSIONS: PCS patients weaned from VA-ECMO after four-seven days of support had significantly less mortality compared with those with shorter or longer mechanical support.
Cardiac Surgery S Anna Hospital Catanzaro Italy
Cardiothoracic Department University Hospital of Udine Udine Italy
Department of Cardiac Surgery Sahlgrenska University Hospital Gothenburg Sweden
Department of Cardiothoracic Surgery Golden Jubilee National Hospital Glasgow United Kingdom
Department of Cardiothoracic Surgery Münster University Hospital Münster Germany
Department of Cardiothoracic Surgery University of Lund Lund Sweden
Department of Cardiovascular Surgery Universitätsklinikum Düsseldorf Düsseldorf Germany
Department of Cardiovascular Surgery Ziekenhuis Oost Limburg Genk Belgium
Department of Surgery University of Turku Turku Finland
Department of Thoracic and Cardio Vascular Surgery University Hospital Jean Minjoz Besançon France
Division of Cardiac Surgery Ospedali Riuniti Trieste Italy
Division of Cardiothoracic and Vascular Surgery Pontchaillou University Hospital Rennes France
Division of Cardiothoracic and Vascular Surgery Robert Debré University Hospital Reims France
Hamburg University Heart Center Hamburg Germany
Heart and Lung Center Helsinki University Hospital Helsinki Finland
Institute of Clinical and Experimental Medicine Prague Czech Republic
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22003829
- 003
- CZ-PrNML
- 005
- 20220127145822.0
- 007
- ta
- 008
- 220113s2021 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1053/j.jvca.2020.11.003 $2 doi
- 035 __
- $a (PubMed)33250434
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Mariscalco, Giovanni $u Department of Intensive Care Medicine and Cardiac Surgery, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom. Electronic address: giovannimariscalco@yahoo.it
- 245 10
- $a Duration of Venoarterial Extracorporeal Membrane Oxygenation and Mortality in Postcardiotomy Cardiogenic Shock / $c G. Mariscalco, Z. El-Dean, H. Yusuff, T. Fux, AM. Dell'Aquila, K. Jónsson, S. Ragnarsson, A. Fiore, M. Dalén, D. di Perna, G. Gatti, T. Juvonen, S. Zipfel, A. Perrotti, K. Bounader, K. Alkhamees, A. Loforte, A. Lechiancole, M. Pol, C. Spadaccio, M. Pettinari, D. De Keyzer, H. Welp, D. Maselli, A. Lichtenberg, VG. Ruggieri, F. Biancari, PC-ECMO Group
- 520 9_
- $a OBJECTIVE: The optimal duration of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in patients affected by postcardiotomy cardiogenic shock (PCS) remains controversial. The present study was conducted to investigate the effect of VA-ECMO duration on hospital outcomes. DESIGN: Retrospective analysis of an international registry. SETTING: Multicenter study including 19 tertiary university hospitals. PARTICIPANTS: Between January 2010 and March 2018, data on PCS patients receiving VA-ECMO were retrieved from the multicenter PC-ECMO registry. INTERVENTIONS: Patients were stratified according to the following different durations of VA-ECMO therapy: ≤three days, four-to-seven days, eight-to-ten days, and >ten days. MEASUREMENTS AND MAIN RESULTS: A total of 725 patients, with a mean age of 62.9 ± 12.9 years, were included. The mean duration of VA-ECMO was 7.1 ± 6.3 days (range 0-39 d), and 39.4% of patients were supported for ≤three days, 29.1% for four-seven days, 15.3% for eight-ten days, and finally 20.7% for >ten days. A total of 391 (53.9%) patients were weaned from VA-ECMO successfully; however, 134 (34.3%) of those patients died before discharge. Multivariate logistic regression showed that prolonged duration of VA-ECMO therapy (four-seven days: adjusted rate 53.6%, odds ratio [OR] 0.28, 95% confidence interval [CI] 0.18-0.44; eight-ten days: adjusted rate 61.3%, OR 0.51, 95% CI 0.29-0.87; and >ten days: adjusted rate 59.3%, OR 0.49, 95% CI 0.31-0.81) was associated with lower risk of mortality compared with VA-ECMO lasting ≤three days (adjusted rate 78.3%). Patients requiring VA-ECMO therapy for eight-ten days (OR 1.96, 95% CI 1.15-3.33) and >10 days (OR 1.85, 95% CI 1.14-3.02) had significantly greater mortality compared with those on VA-ECMO for 4 to 7 days. CONCLUSIONS: PCS patients weaned from VA-ECMO after four-seven days of support had significantly less mortality compared with those with shorter or longer mechanical support.
- 650 _2
- $a senioři $7 D000368
- 650 12
- $a mimotělní membránová oxygenace $7 D015199
- 650 _2
- $a mortalita v nemocnicích $7 D017052
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 12
- $a kardiogenní šok $x mortalita $x terapie $7 D012770
- 650 _2
- $a centra terciární péče $7 D062606
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a multicentrická studie $7 D016448
- 700 1_
- $a El-Dean, Zein $u Department of Intensive Care Medicine and Cardiac Surgery, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom
- 700 1_
- $a Yusuff, Hakeem $u Department of Intensive Care Medicine and Cardiac Surgery, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom
- 700 1_
- $a Fux, Thomas $u Department of Molecular Medicine and Surgery, Department of Cardiac Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
- 700 1_
- $a Dell'Aquila, Angelo M $u Department of Cardiothoracic Surgery, Münster University Hospital, Münster, Germany
- 700 1_
- $a Jónsson, Kristján $u Department of Cardiac Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
- 700 1_
- $a Ragnarsson, Sigurdur $u Department of Cardiothoracic Surgery, University of Lund, Lund, Sweden
- 700 1_
- $a Fiore, Antonio $u Department of Cardiothoracic Surgery, Henri Mondor University Hospital, AP-HP, Paris-Est University, Créteil, France
- 700 1_
- $a Dalén, Magnus $u Department of Molecular Medicine and Surgery, Department of Cardiac Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
- 700 1_
- $a di Perna, Dario $u Division of Cardiothoracic and Vascular Surgery, Robert Debré University Hospital, Reims, France
- 700 1_
- $a Gatti, Giuseppe $u Division of Cardiac Surgery, Ospedali Riuniti, Trieste, Italy
- 700 1_
- $a Juvonen, Tatu $u Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland; Research Unit of Surgery, Anesthesiology and Critical Care, Faculty of Medicine, University of Oulu, Oulu, Finland
- 700 1_
- $a Zipfel, Svante $u Hamburg University Heart Center, Hamburg, Germany
- 700 1_
- $a Perrotti, Andrea $u Department of Thoracic and Cardio-Vascular Surgery, University Hospital Jean Minjoz, Besançon, France
- 700 1_
- $a Bounader, Karl $u Division of Cardiothoracic and Vascular Surgery, Pontchaillou University Hospital, Rennes, France
- 700 1_
- $a Alkhamees, Khalid $u Prince Sultan Cardiac Center, Al Hassa, Saudi Arabia
- 700 1_
- $a Loforte, Antonio $u Department of Cardiothoracic, Transplantation and Vascular Surgery, S. Orsola Hospital, University of Bologna, Bologna, Italy
- 700 1_
- $a Lechiancole, Andrea $u Cardiothoracic Department, University Hospital of Udine, Udine, Italy
- 700 1_
- $a Pol, Marek $u Institute of Clinical and Experimental Medicine, Prague, Czech Republic
- 700 1_
- $a Spadaccio, Cristiano $u Department of Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, United Kingdom
- 700 1_
- $a Pettinari, Matteo $u Department of Cardiovascular Surgery, Ziekenhuis Oost-Limburg, Genk, Belgium
- 700 1_
- $a De Keyzer, Dieter $u Department of Cardiovascular Surgery, Ziekenhuis Oost-Limburg, Genk, Belgium
- 700 1_
- $a Welp, Henryk $u Department of Cardiothoracic Surgery, Münster University Hospital, Münster, Germany
- 700 1_
- $a Maselli, Daniele $u Cardiac Surgery, S. Anna Hospital, Catanzaro, Italy
- 700 1_
- $a Lichtenberg, Artur $u Department of Cardiovascular Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany
- 700 1_
- $a Ruggieri, Vito G $u Division of Cardiothoracic and Vascular Surgery, Robert Debré University Hospital, Reims, France
- 700 1_
- $a Biancari, Fausto $u Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland; Research Unit of Surgery, Anesthesiology and Critical Care, Faculty of Medicine, University of Oulu, Oulu, Finland; Department of Surgery, University of Turku, Turku, Finland
- 710 2_
- $a PC-ECMO Group
- 773 0_
- $w MED00002568 $t Journal of cardiothoracic and vascular anesthesia $x 1532-8422 $g Roč. 35, č. 9 (2021), s. 2662-2668
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/33250434 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20220113 $b ABA008
- 991 __
- $a 20220127145819 $b ABA008
- 999 __
- $a ok $b bmc $g 1751330 $s 1154978
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2021 $b 35 $c 9 $d 2662-2668 $e 20201105 $i 1532-8422 $m Journal of cardiothoracic and vascular anesthesia $n J Cardiovasc Vasc Anesth $x MED00002568
- LZP __
- $a Pubmed-20220113
