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COVID-19 pandemic, mechanical reperfusion and 30-day mortality in ST elevation myocardial infarction
G. De Luca, M. Algowhary, B. Uguz, DC. Oliveira, V. Ganyukov, Z. Zimbakov, M. Cercek, LO. Jensen, PH. Loh, L. Calmac, G. Roura-Ferrer, A. Quadros, M. Milewski, F. Scotto di Uccio, C. von Birgelen, F. Versaci, J. Ten Berg, G. Casella, ASL. Wong,...
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, multicentrická studie
NLK
ProQuest Central
od 1996-01-01 do Před 3 měsíci
Health & Medicine (ProQuest)
od 1996-01-01 do Před 3 měsíci
- MeSH
- čas zasáhnout při rozvinutí nemoci trendy MeSH
- časové faktory MeSH
- COVID-19 * MeSH
- hodnocení rizik MeSH
- incidence MeSH
- infarkt myokardu s elevacemi ST úseků diagnóza mortalita terapie MeSH
- kardiologové trendy MeSH
- koronární angioplastika škodlivé účinky mortalita trendy MeSH
- lékařská praxe - způsoby provádění trendy MeSH
- lidé středního věku MeSH
- lidé MeSH
- mortalita v nemocnicích trendy MeSH
- registrace MeSH
- retrospektivní studie MeSH
- rizikové faktory MeSH
- senioři MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
OBJECTIVE: The initial data of the International Study on Acute Coronary Syndromes - ST Elevation Myocardial Infarction COVID-19 showed in Europe a remarkable reduction in primary percutaneous coronary intervention procedures and higher in-hospital mortality during the initial phase of the pandemic as compared with the prepandemic period. The aim of the current study was to provide the final results of the registry, subsequently extended outside Europe with a larger inclusion period (up to June 2020) and longer follow-up (up to 30 days). METHODS: This is a retrospective multicentre registry in 109 high-volume primary percutaneous coronary intervention (PPCI) centres from Europe, Latin America, South-East Asia and North Africa, enrolling 16 674 patients with ST segment elevation myocardial infarction (STEMI) undergoing PPPCI in March/June 2019 and 2020. The main study outcomes were the incidence of PPCI, delayed treatment (ischaemia time >12 hours and door-to-balloon >30 min), in-hospital and 30-day mortality. RESULTS: In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio 0.843, 95% CI 0.825 to 0.861, p<0.0001). This reduction was significantly associated with age, being higher in older adults (>75 years) (p=0.015), and was not related to the peak of cases or deaths due to COVID-19. The heterogeneity among centres was high (p<0.001). Furthermore, the pandemic was associated with a significant increase in door-to-balloon time (40 (25-70) min vs 40 (25-64) min, p=0.01) and total ischaemia time (225 (135-410) min vs 196 (120-355) min, p<0.001), which may have contributed to the higher in-hospital (6.5% vs 5.3%, p<0.001) and 30-day (8% vs 6.5%, p=0.001) mortality observed during the pandemic. CONCLUSION: Percutaneous revascularisation for STEMI was significantly affected by the COVID-19 pandemic, with a 16% reduction in PPCI procedures, especially among older patients (about 20%), and longer delays to treatment, which may have contributed to the increased in-hospital and 30-day mortality during the pandemic. TRIAL REGISTRATION NUMBER: NCT04412655.
Cardiology Department Garcia de Orta Hospital Almada Portugal
Cardiology Division Ospedale F Spaziani Frosinone Italy
Cardiology Division Ospedale Fabrizio Spaziani Roma Italy
Cardiology Hopital Erasmus Universitè Libre de Bruxelles Bruxelles Belgium
Cardiology Institute Istanbul University Istanbul Turkey
Cardiology Maastricht University Hospital Maastricht The Netherlands
Cardiology Medical Centre Alkmaar Alkmaar The Netherlands
Cardiology National Heart Centre Singapore Singapore
Cardiology Nuovo Ospedale degli Infermi ASL Biella Biella italy
Cardiology Ospedale Alessandro Manzoni Lecco Italy
Cardiology Ospedale di Bolzano Bolzano Italy
Cardiology Ospedale Maggiore Bologna Bologna Italy
Cardiology Radboud UMC Nijmegen The Netherlands
Cardiology Tyumen Research Centre Tyumen Russia
Cardiovascular Department Pelita Harapan University Tangerang Indonesia
Center for Cardiovascular Diseases Ohrid University Hospital Ohrid Macedonia
Central Hospital Medical University of Lodz Lodz Poland
Centre for Intensive Internal Medicine University Medical Centre Ljubljana Slovenia
Centre Hospitalier d Antibes Juan les Pins Antibes France
Clinic Emergency Hospital University of Bucharest Bucuresti Romania
Clinical and Experimental Interventional Cardiology Saarland University Saarbrucken Germany
Complexo Hospetaliero Universitario La Coruna La Coruna Spain
Department of Cardiology AOU Maggiore della Carità Eastern Piedmont University Novara Italy
Department of Cardiology Bezmialem Vakıf University İstanbul Istanbul Turkey
Department of Cardiology Hospital Clinico Universitario Universidad de Valencia Valencia Spain
Department of Cardiology Hospital de Santa Cruz CHLO Nova Medical School CEDOC Carnaxide Portugal
Department of Cardiology Hospital Universitari Germans Trias i Pujol Badalona Spain
Department of Cardiology Hospital Universitari i Politecnic La Fe Valencia Spain
Department of Cardiology INSERM Délégation Régionale Paris 7 Bagnolet France
Department of Cardiology Otamendi Hospital Buenos Aires Argentina
Department of Cardiology Queen ElizabethHospital University of Hong Kong Hong Kong Hong Kong
Department of Cardiology Queen Mary Hospital Hong Kong Hong Kong
Department of Cardiology S Maria Goretti Hospital Latina Italy
Department of Cardiology Singapore Health Service Singapore
Department of Cardiology Sint Antonius Ziekenhuis Nieuwegein The Netherlands
Department of Cardiology University Hospital Virgen de la Victoria Malaga Spain
Department of Cardiology University of Patras Patras Greece
Department of Cardiology University of Zagreb Zagreb Croatia
Department of Cardiovascular Medicine University Hospital Prague Prague Czech Republic
Department of Heart and Vascular Surgery Kemerovo Cardiology Center Кемерово Russia
Department of Statistical Sciences University of Padova Padova Italy
Department of Translational Medicine Eastern Piedmont University Novara Italy
Division of Cardiology ASL 3 Reggio Emilia Reggio Emilia Italy
Division of Cardiology Assiut University Assiut Egypt
Division of Cardiology Attikon Clinic Athens Greece
Division of Cardiology Azienda Ospedaliera Ospedali Riuniti Marche Nord Ancona Italy
Division of cardiology Blida University Hospital Blida Algeria
Division of Cardiology Bursa City Hospital Bursa Turkey
Division of Cardiology Consorcio Sanitario de Tenerife Santa Cruz de Tenerife Spain
Division of Cardiology Cordoba Hospital Cordoba Argentina
Division of Cardiology Eskisehir Osmangazi Universitesi Eskisehir Turkey
Division of Cardiology General Hospital of Athens Alexandra Athens Greece
Division of Cardiology Groupe Hospitalier Mutualiste de Grenoble Grenoble France
Division of Cardiology Heart Centre Turku Turku Finland
Division of Cardiology Hospital Complex of Toledo Toledo Spain
Division of Cardiology Hospital de Cabueñes Gijon Spain
Division of Cardiology Hospital de Santo António Porto Portugal
Division of Cardiology Hospital Puerta de Hierro Mahadahonda Barcelona Spain
Division of Cardiology Iraklion University Hospital Heraklion Greece
Division of Cardiology Kontantopoulion Hospital Athens Athens Greece
Division of Cardiology Lille University Hospital Center Lille France
Division of Cardiology Medellin Clinic Universidad UPB Medellin Colombia
Division of Cardiology Medical University of Silesia in Katowice Katowice Poland
Division of Cardiology Odense Universitetshospital Odense Denmark
Division of Cardiology Ospedale Civico Arnas Palermo Italy
Division of Cardiology Ospedale del Mare Napoli Italy
Division of Cardiology Ospedale G Moscati Aversa Aversa Italy
Division of Cardiology Ospedale S Anna Ferrara Ferrara Italy
Division of Cardiology Ospedale Santa Chiara di Trento Trento Italy
Division of Cardiology Ospedale Santa Maria delle Grazie Pozzuoli Naples Italy
Division of Cardiology Oulu University Hospital Oulu Finland
Division of cardiology Sassari University Hospital Sassari Italy
Division of Cardiology University of Salerno Salerno Italy
Division of Cardiology Utrecht University Utrecht The Netherlands
Division of Cardiology Villa dei fiori Srl Acerra Italy
Hospital Universitario Puerta del Mar Servicio de Cardiología Cadiz Spain
Instituto Cardiovascular de Buenos Aires Buenos Aires Argentina
Instituto de Cardiología de Corrientes Juana Francisca Cabral Corrientes Argentina
Instituto de Cardiologia Integral Montevideo Uruguay
Instituto de Cardiologia Rio Grande do Sul State Department of Health Porto Alegre Brazil
Instituto de Cardiologia Santa Catarina Praia Comprida Sao Jose Brazil
Interventional Cardiology Unit Azienda Ospedaliera Sanitaria Parma Parma Italy
Interventional Cardiology Unit Bellvitge University Hospital L'Hospitalet de Llobregat Spain
Ospedali Riuniti Brescia Italy
Pronto de Socorro Cardiologico Centro PROCAPE Prof Tavares Recife Brazil
SOD Cardiologia Emodinamica UTIC Azienda Ospedali Riuniti Presidio 'GM Lancisi' Ancona Italy
University Clinic for Cardiology Ss Cyril and Methodius University in Skopje Skopje Macedonia
University Hospital Brno Masaryk University Brno Czech Republic
Citace poskytuje Crossref.org
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- $a Oliveira, Dinaldo C $u Pronto de Socorro Cardiologico, Centro PROCAPE Prof. Tavares, Recife, Brazil
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- $a Ganyukov, Vladimir $u Department of Heart and Vascular Surgery, Kemerovo Cardiology Center, Кемерово, Russia
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- $a Zimbakov, Zan $u University Clinic for Cardiology, Ss Cyril and Methodius University in Skopje, Skopje, Macedonia
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- $a Cercek, Miha $u Centre for Intensive Internal Medicine, University Medical Centre, Ljubljana, Slovenia
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- $a Jensen, Lisette Okkels $u Division of Cardiology, Odense Universitetshospital, Odense, Denmark
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- $a Loh, Poay Huan $u Department of Cardiology, Singapore Health Service, Singapore
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- $a Calmac, Lucian $u Clinic Emergency Hospital, University of Bucharest, Bucuresti, Romania
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- $a Quadros, Alexandre $u Instituto de Cardiologia, Rio Grande do Sul State Department of Health, Porto Alegre, Brazil
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- $a Milewski, Marek $u Division of Cardiology, Medical University of Silesia in Katowice, Katowice, Poland
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- $a Scotto di Uccio, Fortunato $u Division of Cardiology, Ospedale del Mare, Napoli, Italy
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- $a Versaci, Francesco $u Department of Cardiology, S Maria Goretti Hospital, Latina, Italy
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- $a Ten Berg, Jurriën $u Department of Cardiology, Sint Antonius Ziekenhuis, Nieuwegein, The Netherlands
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- $a Kala, Petr $u University Hospital Brno, Masaryk University, Brno, Czech Republic
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- $a Kang-Yin Lee, Michael $u Department of Cardiology, Queen ElizabethHospital University of Hong Kong, Hong Kong, Hong Kong
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- $a Juzar, Dafsah A $u Department of cardiology and Vascular Medicine, National Cardiovascular Center 'Harapan Kita', Jakarta, Indonesia
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- $a de Moura Joaquim, Rodrigo $u Instituto de Cardiologia, Santa Catarina Praia Comprida, Sao Jose, Brazil
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