Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

cfDNA Changes in Maximal Exercises as a Sport Adaptation Predictor

K. Humińska-Lisowska, J. Mieszkowski, A. Kochanowicz, B. Stankiewicz, B. Niespodziński, P. Brzezińska, K. Ficek, E. Kemerytė-Ivanauskienė, P. Cięszczyk

. 2021 ; 12 (8) : . [pub] 20210812

Language English Country Switzerland

Document type Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc22012293

Changes of circulating free plasma DNA (cfDNA) are associated with different types of tissue injury, including those induced by intensive aerobic and anaerobic exercises. Observed changes are dependent from induced inflammation, and thus it may be a potential marker for athletic overtraining. We aimed to identify the response of cfDNA to different types of exercise, with association to exercise intensity as a potential marker of exercise load. Fifty volunteers (25 athletes and 25 physically active men) were assigned to the study and performed maximal aerobic (Bruce test) and anaerobic (Wingate Anaerobic Test) test. Blood samples for cfDNA analysis were collected at four time-points: before, 2-5 min after, 30 min after and 60 min after each type of maximal physical activity. The two-way ANOVA revealed a significant effect of group factor on serum cfDNA concentrations (32.15% higher concentration of cfDNA in the athletes). In turn the results of the post hoc test for the interaction of the repeated measures factor and the group showed that while the concentration of cfDNA decreased by 40.10% in the period from 30 min to 60 min after exercise in the control group, the concentration of cfDNA in the group of athletes remained at a similar level. Our analysis presents different responses depending on the intensity and duration of exercise. Our observations imply that formation of cfDNA is associated with response to physical activity but only during maximal effort.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc22012293
003      
CZ-PrNML
005      
20220506130838.0
007      
ta
008      
220425s2021 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/genes12081238 $2 doi
035    __
$a (PubMed)34440412
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Humińska-Lisowska, Kinga $u Faculty of Physical Education, Gdańsk University of Physical Education and Sport, 80-336 Gdansk, Poland $1 https://orcid.org/0000000300340809
245    10
$a cfDNA Changes in Maximal Exercises as a Sport Adaptation Predictor / $c K. Humińska-Lisowska, J. Mieszkowski, A. Kochanowicz, B. Stankiewicz, B. Niespodziński, P. Brzezińska, K. Ficek, E. Kemerytė-Ivanauskienė, P. Cięszczyk
520    9_
$a Changes of circulating free plasma DNA (cfDNA) are associated with different types of tissue injury, including those induced by intensive aerobic and anaerobic exercises. Observed changes are dependent from induced inflammation, and thus it may be a potential marker for athletic overtraining. We aimed to identify the response of cfDNA to different types of exercise, with association to exercise intensity as a potential marker of exercise load. Fifty volunteers (25 athletes and 25 physically active men) were assigned to the study and performed maximal aerobic (Bruce test) and anaerobic (Wingate Anaerobic Test) test. Blood samples for cfDNA analysis were collected at four time-points: before, 2-5 min after, 30 min after and 60 min after each type of maximal physical activity. The two-way ANOVA revealed a significant effect of group factor on serum cfDNA concentrations (32.15% higher concentration of cfDNA in the athletes). In turn the results of the post hoc test for the interaction of the repeated measures factor and the group showed that while the concentration of cfDNA decreased by 40.10% in the period from 30 min to 60 min after exercise in the control group, the concentration of cfDNA in the group of athletes remained at a similar level. Our analysis presents different responses depending on the intensity and duration of exercise. Our observations imply that formation of cfDNA is associated with response to physical activity but only during maximal effort.
650    12
$a fyziologická adaptace $7 D000222
650    _2
$a biologické markery $x krev $7 D015415
650    _2
$a studie případů a kontrol $7 D016022
650    _2
$a volné cirkulující nukleové kyseliny $x krev $7 D000073888
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    12
$a sporty $7 D013177
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Mieszkowski, Jan $u Faculty of Physical Education, Gdańsk University of Physical Education and Sport, 80-336 Gdansk, Poland $u Faculty of Physical Education and Sport, Charles University, 162 52 Prague, Czech Republic
700    1_
$a Kochanowicz, Andrzej $u Faculty of Physical Education, Gdańsk University of Physical Education and Sport, 80-336 Gdansk, Poland
700    1_
$a Stankiewicz, Błażej $u Institute of Physical Education, Kazimierz Wielki University, 85-064 Bydgoszcz, Poland
700    1_
$a Niespodziński, Bartłomiej $u Institute of Physical Education, Kazimierz Wielki University, 85-064 Bydgoszcz, Poland $1 https://orcid.org/0000000189923730
700    1_
$a Brzezińska, Paulina $u Faculty of Physical Education, Gdańsk University of Physical Education and Sport, 80-336 Gdansk, Poland
700    1_
$a Ficek, Krzysztof $u Faculty of Physiotherapy, The Jerzy Kukuczka Academy of Physical Education in Katowice, 40-065 Katowice, Poland $1 https://orcid.org/0000000230279984
700    1_
$a Kemerytė-Ivanauskienė, Eglė $u Academy of Education, Vytautas Magnus University, 03111 Vilnius, Lithuania
700    1_
$a Cięszczyk, Paweł $u Faculty of Physical Education, Gdańsk University of Physical Education and Sport, 80-336 Gdansk, Poland
773    0_
$w MED00174652 $t Genes $x 2073-4425 $g Roč. 12, č. 8 (2021)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/34440412 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20220425 $b ABA008
991    __
$a 20220506130830 $b ABA008
999    __
$a ok $b bmc $g 1789747 $s 1163494
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 12 $c 8 $e 20210812 $i 2073-4425 $m Genes $n Genes $x MED00174652
LZP    __
$a Pubmed-20220425

Find record

Citation metrics

Archiving options