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Topical bimatoprost in the treatment of eyelash loss in alopecia totalis and universalis: A prospective, open-label study
J. Ricar, P. Cetkovska, M. Hordinsky, R. Ricarova
Language English Country United States
Document type Journal Article
Grant support
CZ.02.1.01/0.0/0.0/16_019/0000787
Ministry of Education Youth and Sports of the Czech Republic
PubMed
35278027
DOI
10.1111/dth.15438
Knihovny.cz E-resources
- MeSH
- Alopecia Areata * MeSH
- Alopecia diagnosis drug therapy MeSH
- Bimatoprost adverse effects MeSH
- Humans MeSH
- Eyelashes * MeSH
- Prospective Studies MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
Bimatoprost is a synthetic prostaglandin structural analogue used among other indications to increase eyelash growth. The aim of this prospective, open-label study was to evaluate the safety and efficacy of topical bimatoprost in the treatment of eyelash loss in alopecia areata totalis (AT) and universalis (AU). Study subjects applied ophthalmic bimatoprost (0.3 mg/ml) solution to the eyelid margins once nightly for at least 12 weeks (mean treatment period was 30.6 weeks). A total of 16 out of 17 subjects completed the study. Only the subjects with eyelashes present at baseline experienced an increase in eyelash length and thickness. No new eyelash regrowth was induced. In patients with AT and AU topical bimatoprost affected existing eyelashes, but failed to induce regrowth of new eyelashes.
Biomedical Center Faculty of Medicine in Pilsen Charles University Pilsen Czech Republic
Department of Dermatology University of Minnesota Minneapolis Minnesota USA
Department of Ophthalmology Faculty of Medicine in Pilsen Charles University Pilsen Czech Republic
References provided by Crossref.org
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- $a Bimatoprost is a synthetic prostaglandin structural analogue used among other indications to increase eyelash growth. The aim of this prospective, open-label study was to evaluate the safety and efficacy of topical bimatoprost in the treatment of eyelash loss in alopecia areata totalis (AT) and universalis (AU). Study subjects applied ophthalmic bimatoprost (0.3 mg/ml) solution to the eyelid margins once nightly for at least 12 weeks (mean treatment period was 30.6 weeks). A total of 16 out of 17 subjects completed the study. Only the subjects with eyelashes present at baseline experienced an increase in eyelash length and thickness. No new eyelash regrowth was induced. In patients with AT and AU topical bimatoprost affected existing eyelashes, but failed to induce regrowth of new eyelashes.
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