-
Je něco špatně v tomto záznamu ?
New Uses of Melatonin as a Drug; A Review
M. Pohanka
Jazyk angličtina Země Spojené arabské emiráty
Typ dokumentu časopisecké články, přehledy
- MeSH
- cirkadiánní rytmus fyziologie MeSH
- lidé MeSH
- melatonin * metabolismus farmakologie terapeutické užití MeSH
- melatoninové receptory MeSH
- poruchy spánku a bdění * farmakoterapie MeSH
- spánek MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Melatonin is a simple compound called N-acetyl-5-methoxy tryptamine and is known as a hormone controlling the circadian rhythm. Melatonin is produced by the human body naturally. The production of melatonin increases in the evening, causing a state of sleep at night and wakefulness during the day. Melatonin interacts with melatonin receptors MT1 and MT2, but it was revealed that melatonin is a strong antioxidant and it also has a role in the regulation of the cell cycle. Melatonin is now used as a medicine to treat some types of sleep disorders. Moreover, recent research suggests that it can also be utilized for other purposes, such as prevention from chemical exposure and treatment of various diseases, including cancer, neurodegenerative disorders, etc. This review summarizes the basic facts and direction of the current research on melatonin. The existing literature was scrutinized for this review.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22019508
- 003
- CZ-PrNML
- 005
- 20220804135723.0
- 007
- ta
- 008
- 220720s2022 ts f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.2174/0929867329666220105115755 $2 doi
- 035 __
- $a (PubMed)34986763
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ts
- 100 1_
- $a Pohanka, Miroslav $u Faculty of Military Health Sciences, University of Defense, Trebesska 1575, Hradec Kralove CZ-50001, Czech Republic
- 245 10
- $a New Uses of Melatonin as a Drug; A Review / $c M. Pohanka
- 520 9_
- $a Melatonin is a simple compound called N-acetyl-5-methoxy tryptamine and is known as a hormone controlling the circadian rhythm. Melatonin is produced by the human body naturally. The production of melatonin increases in the evening, causing a state of sleep at night and wakefulness during the day. Melatonin interacts with melatonin receptors MT1 and MT2, but it was revealed that melatonin is a strong antioxidant and it also has a role in the regulation of the cell cycle. Melatonin is now used as a medicine to treat some types of sleep disorders. Moreover, recent research suggests that it can also be utilized for other purposes, such as prevention from chemical exposure and treatment of various diseases, including cancer, neurodegenerative disorders, etc. This review summarizes the basic facts and direction of the current research on melatonin. The existing literature was scrutinized for this review.
- 650 _2
- $a cirkadiánní rytmus $x fyziologie $7 D002940
- 650 _2
- $a lidé $7 D006801
- 650 12
- $a melatonin $x metabolismus $x farmakologie $x terapeutické užití $7 D008550
- 650 _2
- $a melatoninové receptory $7 D044094
- 650 _2
- $a spánek $7 D012890
- 650 12
- $a poruchy spánku a bdění $x farmakoterapie $7 D012893
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 773 0_
- $w MED00001274 $t Current medicinal chemistry $x 1875-533X $g Roč. 29, č. 20 (2022), s. 3622-3637
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/34986763 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20220720 $b ABA008
- 991 __
- $a 20220804135716 $b ABA008
- 999 __
- $a ok $b bmc $g 1822912 $s 1170751
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2022 $b 29 $c 20 $d 3622-3637 $e - $i 1875-533X $m Current medicinal chemistry $n Curr Med Chem $x MED00001274
- LZP __
- $a Pubmed-20220720
