Background: A new silver-based dressing has been designed to reduce surgical sited infections. Patients and Methods: A prospective multicenter observational study was conducted from January 2020 to October 2021. Patients with and without silver-based dressing after surgical incision were observed and their data analyzed. The study aimed to assess the incidence of incisional surgical site infection and primary healing after general surgery procedures. Results: Overall, 218 patients with silver-based (n = 109) and conventional silver-free dressing (n = 109) were analyzed. Surgical site infection (SSI) and primary incision healing were reported in 10 (9.2%) versus 21 (19.3%) (p = 0.037) and in 95 (87.2%) versus 86 (78.9%) (p = 0.107) patients treated with and without silver-based dressing, respectively. Conclusions: Silver-based dressing demonstrated a lower incidence of incisional SSI and improved primary healing in comparison with patients in whom conventional non-silver-based dressing has been used.

Cardiocenter University Hospital Královské Vinohrady 3rd Faculty of Medicine Charles University Prague Czech Republic

Department of Anaesthesiology and Resuscitation University Hospital Královské Vinohrady 3rd Faculty of Medicine Charles University Prague Czech Republic

Department of Surgery 1 Faculty of Medicine and Dentistry Palacký University and University Hospital Olomouc Czech Republic

Department of Surgery 1st Faculty of Medicine Charles University and Thomayer University Hospital Prague Czech Republic

Department of Surgery The University Hospital Brno Czech Republic

Department of Surgery University Hospital Královské Vinohrady 3rd Faculty of Medicine Charles University Prague Czech Republic

Department of Vascular Surgery National Institute for Cardiovascular Diseases Bratislava Slovak Republic

Faculty of Biomedical Engineering Czech Technical University Prague Kladno Czech Republic

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$a Silver-Based Dressings in the Prevention of the Incisional Surgical Site Infection: A Prospective Multicenter Observational Controlled Trial / $c K. Lawrie, P. Waldauf, P. Baláž, J. Drozd, P. Brat'ka, M. Loveček, D. Klos, P. Skalický, P. Peňázová Kurečková, O. Kráčmar, Z. Kala, V. Makajevová, L. Hodačová, J. Šimša, R. Gürlich

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$a Background: A new silver-based dressing has been designed to reduce surgical sited infections. Patients and Methods: A prospective multicenter observational study was conducted from January 2020 to October 2021. Patients with and without silver-based dressing after surgical incision were observed and their data analyzed. The study aimed to assess the incidence of incisional surgical site infection and primary healing after general surgery procedures. Results: Overall, 218 patients with silver-based (n = 109) and conventional silver-free dressing (n = 109) were analyzed. Surgical site infection (SSI) and primary incision healing were reported in 10 (9.2%) versus 21 (19.3%) (p = 0.037) and in 95 (87.2%) versus 86 (78.9%) (p = 0.107) patients treated with and without silver-based dressing, respectively. Conclusions: Silver-based dressing demonstrated a lower incidence of incisional SSI and improved primary healing in comparison with patients in whom conventional non-silver-based dressing has been used.

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$a Waldauf, Petr $u Department of Anaesthesiology and Resuscitation, University Hospital Královské Vinohrady, Third Faculty of Medicine, Charles University, Prague, Czech Republic

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$a Baláž, Peter $u Department of Surgery, University Hospital Královské Vinohrady, Third Faculty of Medicine, Charles University, Prague, Czech Republic $u Cardiocenter, University Hospital Královské Vinohrady, Third Faculty of Medicine, Charles University, Prague, Czech Republic $u Department of Vascular Surgery, National Institute for Cardiovascular Diseases, Bratislava, Slovak Republic

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$a Drozd, Jan $u Department of Surgery, University Hospital Královské Vinohrady, Third Faculty of Medicine, Charles University, Prague, Czech Republic

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$a Brat'ka, Petr $u Faculty of Biomedical Engineering Czech Technical University in Prague, Kladno, Czech Republic

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$a Loveček, Martin $u Department of Surgery I, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Czech Republic

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$a Klos, Dušan $u Department of Surgery I, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Czech Republic

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$a Peňázová Kurečková, Petra $u Department of Surgery, The University Hospital Brno, Czech Republic

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$a Kala, Zdeněk $u Department of Surgery, The University Hospital Brno, Czech Republic

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$a Makajevová, Veronika $u Department of Surgery, First Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic

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$a Hodačová, Linda $u Department of Surgery, First Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic

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$a Šimša, Jaromír $u Department of Surgery, First Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic

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$a Gürlich, Robert $u Department of Surgery, University Hospital Královské Vinohrady, Third Faculty of Medicine, Charles University, Prague, Czech Republic

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