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Risk stratification of neurological decompression sickness in divers
M. Sramek, J. Honek, A. Tomek, T. Ruzickova, T. Honek, L. Sefc
Jazyk angličtina Země Slovensko
Typ dokumentu práce podpořená grantem, klinická studie
- MeSH
- dekompresní nemoc * epidemiologie etiologie klasifikace patofyziologie MeSH
- dospělí MeSH
- foramen ovale apertum komplikace MeSH
- lidé MeSH
- plošný screening metody MeSH
- potápění * škodlivé účinky MeSH
- rizikové faktory MeSH
- statistika jako téma MeSH
- syndrom přetrvávajícího fetálního oběhu diagnóza epidemiologie komplikace MeSH
- ultrasonografie dopplerovská transkraniální MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- Publikační typ
- klinická studie MeSH
- práce podpořená grantem MeSH
INTRODUCTION: Patent foramen ovale (PFO) is a risk factor of decompression sickness (DCS). However, data on risk stratification of divers with a PFO are sparse. This study sought to evaluate the risk of neurological DCS (DCSneuro), based on the presence and grade of a right-to-left shunt (RLS). METHODS: A total of 640 divers were screened for a RLS using TCD between 1/2006 and 4/2017. RLS was graded as low, medium, or high grade with two subgroups - after a Valsalva maneuver or at rest. Divers were questioned about their DCS history. Survival analysis techniques were used to assess risk factors for unprovoked DCS. RESULTS: A RLS was found in 258 divers (40.3 %). 44 (17.1 %) divers with a RLS experienced DCSneuro compared to 5 (1.3 %) divers without a RLS (p <0.001). The proportion of DCSneuro increased from 4.6 % in the low-grade RLS subgroup to 57.1 % in the subgroup with high-grade RLS at rest. The hazard ratio for DCSneuro and RLS was11.806 (p <0.001). CONCLUSIONS: Divers with a RLS had a higher risk of DCSneuro and the risk increased with RLS grade. We suggest that TCD is an appropriate method for RLS screening and risk stratification in divers (Tab. 4, Fig. 2, Ref. 29).
Avicena chirurgie s r o Prague Czech Republic
Center for Advanced Preclinical Imaging Charles University Prague Czech Republic
Citace poskytuje Crossref.org
Literatura
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- $a INTRODUCTION: Patent foramen ovale (PFO) is a risk factor of decompression sickness (DCS). However, data on risk stratification of divers with a PFO are sparse. This study sought to evaluate the risk of neurological DCS (DCSneuro), based on the presence and grade of a right-to-left shunt (RLS). METHODS: A total of 640 divers were screened for a RLS using TCD between 1/2006 and 4/2017. RLS was graded as low, medium, or high grade with two subgroups - after a Valsalva maneuver or at rest. Divers were questioned about their DCS history. Survival analysis techniques were used to assess risk factors for unprovoked DCS. RESULTS: A RLS was found in 258 divers (40.3 %). 44 (17.1 %) divers with a RLS experienced DCSneuro compared to 5 (1.3 %) divers without a RLS (p <0.001). The proportion of DCSneuro increased from 4.6 % in the low-grade RLS subgroup to 57.1 % in the subgroup with high-grade RLS at rest. The hazard ratio for DCSneuro and RLS was11.806 (p <0.001). CONCLUSIONS: Divers with a RLS had a higher risk of DCSneuro and the risk increased with RLS grade. We suggest that TCD is an appropriate method for RLS screening and risk stratification in divers (Tab. 4, Fig. 2, Ref. 29).
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