A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).

Annotation

also known as PPHN check the tags HUMANS & INFANT, NEWBORN

DUI

D010547 MeSH Browser

CUI

M0016380

Previous indexing

Ductus Arteriosus, Patent (1966-1979); Hypertension, Pulmonary (1966-1979); Pulmonary Circulation (1966-1979)

History note

1980

Public note

1980