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Early Osteoarthritis Questionnaire (EOAQ): a tool to assess knee osteoarthritis at initial stage
A. Migliore, L. Alekseeva, SR. Avasthi, RR. Bannuru, X. Chevalier, T. Conrozier, S. Crimaldi, GC. de Campos, D. Diracoglu, G. Gigliucci, G. Herrero-Beaumont, G. Iolascon, R. Ionescu, J. Jerosch, J. Lains, E. Maheu, S. Makri, N. Martusevich, M....
Status not-indexed Language English Country England, Great Britain
Document type Journal Article
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PubMed Central
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from 2009-10-01
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- Publication type
- Journal Article MeSH
BACKGROUND: Early stage of osteoarthritis (OA) is characterized by joint stiffness and pain as well as by subclinical structural changes that may affect cartilage, synovium, and bone. At the moment, the lack of a validated definition of early osteoarthritis (EOA) does not allow to make an early diagnosis and adopt a therapeutic strategy to slow disease progression. Also, no questionnaires are available to evaluate the early stage, and therefore this remains an unmet need. OBJECTIVE: Therefore, the purpose of the technical experts panel (TEP) of 'International Symposium of intra-articular treatment' (ISIAT) was to create a specific questionnaire to evaluate and monitor the follow-up and clinical progress of patients affected by early knee OA. DESIGN: The items for the Early Osteoarthritis Questionnaire (EOAQ) were identified according to the following steps: items generation, items reduction, and pre-test submission. METHODS: During the first step, literature has been reviewed and a comprehensive list of items about pain and function in knee EOA was drafted. Then, during the ISIAT (5th edition 2019), the draft has been discussed by the board, which reformulated, deleted, or subdivided some of the items. After the ISIAT symposium, the draft was submitted to 24 subjects affected by knee OA. A score based on the importance and the frequency was created and the items with a score ⩾0.75 were selected. After intermediate evaluation made by a sample of patients, the second and final version of the questionnaire EOAQ was submitted to the whole board for final analysis and acceptance in a second meeting (29 January 2021). RESULTS: After an exhaustive elaboration, the final version of the questionnaire contains two domains (Clinical Features and Patients Reported Outcome) with respectively 2 and 9 questions, for a total of 11 questions. Questions mainly explored the fields of early symptoms and patients reported outcomes. Marginally, the need of the symptoms treatment and the use of painkillers were investigated. CONCLUSIONS: Adoption of diagnostic criteria of early OA is strongly encouraged and a specific questionnaire for the whole management of the clinical features and patients' outcome might really improve the evolution of OA in the early stages of the disease, when the treatment is expected to be more effective.
Chirurgia Ortopedica Mininvasiva e Nuove Tecnologie Humanitas Research Hospital Castellanza Italy
Department of Emergency Medicine Dr Ram Manohar Lohia Hospital Lucknow India
Department of Experimental and Clinical Medicine University of Florence Florence Italy
Department of Family Medicine School of Kinesiology University Western Ontario Ontario ON Canada
Department of Orthopaedics and Traumatology 'Policlinico Tor Vergata' Foundation Rome Italy
Department of Orthopaedics and Traumatology University of Campinas São Paulo Brazil
Department of Rheumatology Belorussian State Medical University Minsk Belarus
EUPATI Graduate and Patient Advocate Brussels Belgium
Institute of Rheumatology Prague Czech Republic
Joint and Bone Research Unit IIS Fundacion Jimenez Diaz UAM Madrid Spain
Orthopaedic Department Johanna Etienne Hospital Neuss Germany
Rheumatology Department AP HP Saint Antoine Hospital Paris France
Rheumatology Unit San Pietro Fatebenefratelli Hospital Rome Italy
Rheumatology Unit San Pietro Fatebenefratelli Hospital Via Cassia 600 00189 Rome Italy
References provided by Crossref.org
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