Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Enhancing Public Health Communication Regarding Vaccine Trials: Design and Development of the Pan-European VACCELERATE Toolkit

CD. Argyropoulos, J. Leckler, J. Salmanton-García, M. Constantinou, A. Alexandrou, S. Themistocleous, E. Noula, G. Shiamakkides, A. Nearchou, FA. Stewart, K. Albus, M. Koniordou, I. Kopsidas, O. Spivak, M. Hellemans, G. Hendrickx, RJ. Davis, AM....

. 2023 ; 9 (-) : e44491. [pub] 20230403

Jazyk angličtina Země Kanada

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc23010504

BACKGROUND: The pan-European VACCELERATE network aims to implement the first transnational harmonized and sustainable vaccine trial Volunteer Registry, being a single entry point for potential volunteers of large-scale vaccine trials across Europe. This work exhibits a set of harmonized vaccine trial-related educational and promotional tools for the general public, designed and disseminated by the pan-European VACCELERATE network. OBJECTIVE: This study primarily aimed to design and develop a standard toolkit to increase positive attitudes and access to trustworthy information for better access and increased recruitment to vaccine trials for the public. More specifically, the produced tools are focused on inclusiveness and equity, and are targeting different population groups, including underserved ones, as potential volunteers for the VACCELERATE Volunteer Registry (older individuals, migrants, children, and adolescents). The promotional and educational material is aligned with the main objectives of the Volunteer Registry to increase public literacy and awareness regarding vaccine-related clinical research or trials and trial participation, including informed consent and legal issues, side effects, and frequently asked questions regarding vaccine trial design. METHODS: Tools were developed per the aims and principles of the VACCELERATE project, focusing on trial inclusiveness and equity, and are adjusted to local country-wise requirements to improve public health communication. The produced tools are selected based on the cognitive theory, inclusiveness, and equity of differently aged and underrepresented groups, and standardized material from several official trustworthy sources (eg, COVID-19 Vaccines Global Access; the European Centre for Disease Prevention and Control; the European Patients' Academy on Therapeutic Innovation; Gavi, the Vaccine Alliance; and the World Health Organization). A team of multidisciplinary specialists (infectious diseases, vaccine research, medicine, and education) edited and reviewed the subtitles and scripts of the educational videos, extended brochures, interactive cards, and puzzles. Graphic designers selected the color palette, audio settings, and dubbing for the video story-tales and implemented QR codes. RESULTS: This study presents the first set of harmonized promotional and educational materials and tools (ie, educational cards, educational and promotional videos, extended brochures, flyers, posters, and puzzles) for vaccine clinical research (eg, COVID-19 vaccines). These tools inform the public about possible benefits and disadvantages of trial participation and build confidence among participants about the safety and efficacy of COVID-19 vaccines and the health care system. This material has been translated into several languages and is intended to be freely and easily accessible to facilitate dissemination among VACCELERATE network participant countries and the European and global scientific, industrial, and public community. CONCLUSIONS: The produced material could help fill knowledge gaps of health care personnel, providing the appropriate future patient education for vaccine trials, and tackling vaccine hesitancy and parents' concerns for potential participation of children in vaccine trials.

Assistance Publique Hopitaux de Paris Université Paris Cité Paris France

Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology Department 1 of Internal Medicine Faculty of Medicine and University Hospital Cologne University of Cologne Cologne Germany

Center for Molecular Medicine Cologne Faculty of Medicine and University Hospital Cologne University of Cologne Cologne Germany

Centre for Experimental Pathogen Host Research School of Medicine University College Dublin Dublin Ireland

Centre of Excellence for Health Immunity and Infections Rigshospitalet University of Copenhagen Copenhagen Denmark

Centro Hospitalar Universitário do Porto Porto Portugal

Centro Nacional de Microbiología Instituto de Salud Carlos 3 Madrid Spain

Clinical Trials Centre Cologne Faculty of Medicine and University Hospital Cologne University of Cologne Cologne Germany

Collaborative Center for Clinical Epidemiology and Outcomes Research Athens Greece

Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases Faculty of Medicine and University Hospital Cologne University of Cologne Cologne Germany

Czech Clinical Research Infrastructure Network Brno Czech Republic

Department of Infectious Diseases and Clinical Microbiology Faculty of Medicine Haceteppe University Ankara Turkey

Department of Infectious Diseases Karolinska University Hospital Stockholm Sweden

Department of Medical Microbiology University Medical Centre Utrecht Utrecht Netherlands

Department of Medicine Division of Infectious Diseases Karolinska Institutet Stockholm Sweden

European Vaccine Initiative Heidelberg Germany

German Centre for Infection Research Partner Site Bonn Cologne Cologne Germany

Hospital La Paz Institute for Health Research Madrid Spain

Infectious Diseases Department of Diagnostic and Public Health University of Verona Verona Italy

Influenza Centre Department of Clinical Science University of Bergen Bergen Norway

Institut National de la Santé et de la Recherche Médicale France Recherche Nord and Sud Sida HIV Hépatites Maladies Infectieuses Émergentes Paris France

Institute of Clinical Medicine Medical Faculty Vilnius University Vilnius Lithuania

Julius Center for Health Sciences and Primary Care University Medical Centre Utrecht Utrecht University Utrecht Netherlands

Masaryk University Brno Czech Republic

Medizinische Universität Wien Vienna Austria

Ministry of Health of Israel Jerusalem Israel

National Koranyi Institute for Pulmonology Budapest Hungary

School of Medicine European University Cyprus Nicosia Cyprus

Servicio Madrileño de Salud Madrid Spain

University Hospital Brno Brno Czech Republic

University Medical Centre Utrecht Utrecht University Utrecht Netherlands

VAXINFECTIO Centre of Evaluation of Vaccination Faculty of Medicine and Health Science Universiteit Antwerpen Antwerp Belgium

Vilnius University Hospital Santaros klinikos Medical Faculty Vilnius University Vilnius Lithuania

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc23010504
003      
CZ-PrNML
005      
20240206144421.0
007      
ta
008      
230718e20230403xxc f 000 0|eng||
009      
AR
024    7_
$a 10.2196/44491 $2 doi
035    __
$a (PubMed)36878478
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxc
100    1_
$a Argyropoulos, Christos D $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0000000220902162
245    10
$a Enhancing Public Health Communication Regarding Vaccine Trials: Design and Development of the Pan-European VACCELERATE Toolkit / $c CD. Argyropoulos, J. Leckler, J. Salmanton-García, M. Constantinou, A. Alexandrou, S. Themistocleous, E. Noula, G. Shiamakkides, A. Nearchou, FA. Stewart, K. Albus, M. Koniordou, I. Kopsidas, O. Spivak, M. Hellemans, G. Hendrickx, RJ. Davis, AM. Azzini, PV. Simon, AJ. Carcas-Sansuan, HH. Askling, S. Vene, JB. Prellezo, E. Álvarez-Barco, AJ. Macken, R. Di Marzo, C. Luís, OF. Olesen, JA. Frias Iniesta, I. Barta, K. Tóth, M. Akova, MMJ. Bonten, M. Cohen-Kandli, RJ. Cox, L. Součková, P. Husa, L. Jancoriene, O. Launay, J. Lundgren, P. Mallon, C. Armeftis, L. Marques, P. Naucler, J. Ochando, E. Tacconelli, P. van Damme, T. Zaoutis, S. Hofstraat, P. Bruijning-Verhagen, M. Zeitlinger, OA. Cornely, ZD. Pana
520    9_
$a BACKGROUND: The pan-European VACCELERATE network aims to implement the first transnational harmonized and sustainable vaccine trial Volunteer Registry, being a single entry point for potential volunteers of large-scale vaccine trials across Europe. This work exhibits a set of harmonized vaccine trial-related educational and promotional tools for the general public, designed and disseminated by the pan-European VACCELERATE network. OBJECTIVE: This study primarily aimed to design and develop a standard toolkit to increase positive attitudes and access to trustworthy information for better access and increased recruitment to vaccine trials for the public. More specifically, the produced tools are focused on inclusiveness and equity, and are targeting different population groups, including underserved ones, as potential volunteers for the VACCELERATE Volunteer Registry (older individuals, migrants, children, and adolescents). The promotional and educational material is aligned with the main objectives of the Volunteer Registry to increase public literacy and awareness regarding vaccine-related clinical research or trials and trial participation, including informed consent and legal issues, side effects, and frequently asked questions regarding vaccine trial design. METHODS: Tools were developed per the aims and principles of the VACCELERATE project, focusing on trial inclusiveness and equity, and are adjusted to local country-wise requirements to improve public health communication. The produced tools are selected based on the cognitive theory, inclusiveness, and equity of differently aged and underrepresented groups, and standardized material from several official trustworthy sources (eg, COVID-19 Vaccines Global Access; the European Centre for Disease Prevention and Control; the European Patients' Academy on Therapeutic Innovation; Gavi, the Vaccine Alliance; and the World Health Organization). A team of multidisciplinary specialists (infectious diseases, vaccine research, medicine, and education) edited and reviewed the subtitles and scripts of the educational videos, extended brochures, interactive cards, and puzzles. Graphic designers selected the color palette, audio settings, and dubbing for the video story-tales and implemented QR codes. RESULTS: This study presents the first set of harmonized promotional and educational materials and tools (ie, educational cards, educational and promotional videos, extended brochures, flyers, posters, and puzzles) for vaccine clinical research (eg, COVID-19 vaccines). These tools inform the public about possible benefits and disadvantages of trial participation and build confidence among participants about the safety and efficacy of COVID-19 vaccines and the health care system. This material has been translated into several languages and is intended to be freely and easily accessible to facilitate dissemination among VACCELERATE network participant countries and the European and global scientific, industrial, and public community. CONCLUSIONS: The produced material could help fill knowledge gaps of health care personnel, providing the appropriate future patient education for vaccine trials, and tackling vaccine hesitancy and parents' concerns for potential participation of children in vaccine trials.
650    _2
$a dítě $7 D002648
650    _2
$a mladiství $7 D000293
650    _2
$a lidé $7 D006801
650    _2
$a senioři $7 D000368
650    12
$a COVID-19 $x prevence a kontrola $7 D000086382
650    _2
$a vakcíny proti COVID-19 $7 D000086663
650    12
$a zdravotnická komunikace $7 D058015
650    12
$a vakcíny $7 D014612
651    _2
$a Evropa $7 D005060
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Leckler, Janina $u Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $1 https://orcid.org/0000000284884338
700    1_
$a Salmanton-García, Jon $u Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $1 https://orcid.org/0000000267668297
700    1_
$a Constantinou, Marinos $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0000000235028041
700    1_
$a Alexandrou, Alexandra $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0009000392124288
700    1_
$a Themistocleous, Sophia $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0000000335610004
700    1_
$a Noula, Evgenia $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0009000857992289
700    1_
$a Shiamakkides, George $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/000000032982169X
700    1_
$a Nearchou, Andria $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0009000902790521
700    1_
$a Stewart, Fiona A $u Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $1 https://orcid.org/0000000210295768
700    1_
$a Albus, Kerstin $u Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $1 https://orcid.org/0000000311244310
700    1_
$a Koniordou, Markela $u Collaborative Center for Clinical Epidemiology and Outcomes Research, Athens, Greece $1 https://orcid.org/0000000260341291
700    1_
$a Kopsidas, Ioannis $u Collaborative Center for Clinical Epidemiology and Outcomes Research, Athens, Greece $1 https://orcid.org/0000000164994807
700    1_
$a Spivak, Orly $u Ministry of Health of Israel, Jerusalem, Israel $1 https://orcid.org/0000000217366696
700    1_
$a Hellemans, Margot $u VAXINFECTIO, Centre of Evaluation of Vaccination, Faculty of Medicine and Health Science, Universiteit Antwerpen, Antwerp, Belgium $1 https://orcid.org/0009000529261559
700    1_
$a Hendrickx, Greet $u VAXINFECTIO, Centre of Evaluation of Vaccination, Faculty of Medicine and Health Science, Universiteit Antwerpen, Antwerp, Belgium $1 https://orcid.org/000000020099272X
700    1_
$a Davis, Ruth Joanna $u Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, Verona, Italy $1 https://orcid.org/0000000193646983
700    1_
$a Azzini, Anna Maria $u Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, Verona, Italy $1 https://orcid.org/0000000271482559
700    1_
$a Simon, Paula Valle $u Hospital La Paz Institute for Health Research, Madrid, Spain $u Servicio Madrileño de Salud, Madrid, Spain $1 https://orcid.org/0000000233999725
700    1_
$a Carcas-Sansuan, Antonio Javier $u Hospital La Paz Institute for Health Research, Madrid, Spain $u Servicio Madrileño de Salud, Madrid, Spain $1 https://orcid.org/0000000318234174
700    1_
$a Askling, Helena Hervius $u Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden $u Department of Medicine, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden $1 https://orcid.org/0000000151559726
700    1_
$a Vene, Sirkka $u Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden $u Department of Medicine, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden $1 https://orcid.org/0000000286555845
700    1_
$a Prellezo, Jana Baranda $u Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain $1 https://orcid.org/0000000290609228
700    1_
$a Álvarez-Barco, Elena $u Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin, Dublin, Ireland $1 https://orcid.org/0000000249039171
700    1_
$a Macken, Alan J $u Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin, Dublin, Ireland $1 https://orcid.org/0000000333208767
700    1_
$a Di Marzo, Romina $u European Vaccine Initiative, Heidelberg, Germany $1 https://orcid.org/0000000287150348
700    1_
$a Luís, Catarina $u European Vaccine Initiative, Heidelberg, Germany $1 https://orcid.org/0000000327484087
700    1_
$a Olesen, Ole F $u European Vaccine Initiative, Heidelberg, Germany $1 https://orcid.org/0000000230252466
700    1_
$a Frias Iniesta, Jesus A $u Hospital La Paz Institute for Health Research, Madrid, Spain $u Servicio Madrileño de Salud, Madrid, Spain $1 https://orcid.org/0000000195389677
700    1_
$a Barta, Imre $u National Koranyi Institute for Pulmonology, Budapest, Hungary $1 https://orcid.org/0000000300675166
700    1_
$a Tóth, Krisztina $u National Koranyi Institute for Pulmonology, Budapest, Hungary $1 https://orcid.org/0009000915595581
700    1_
$a Akova, Murat $u Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Haceteppe University, Ankara, Turkey $1 https://orcid.org/0000000269049473 $7 xx0197408
700    1_
$a Bonten, Marc M J $u Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands $u Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, Netherlands $1 https://orcid.org/0000000290959201
700    1_
$a Cohen-Kandli, Miriam $u Ministry of Health of Israel, Jerusalem, Israel $1 https://orcid.org/0000000215045688
700    1_
$a Cox, Rebecca Jane $u Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway $1 https://orcid.org/0000000283414078
700    1_
$a Součková, Lenka $u Masaryk University, Brno, Czech Republic $u University Hospital Brno, Brno, Czech Republic $u Czech Clinical Research Infrastructure Network, Brno, Czech Republic $1 https://orcid.org/0000000300284464 $7 xx0204153
700    1_
$a Husa, Petr $u Masaryk University, Brno, Czech Republic $u University Hospital Brno, Brno, Czech Republic $u Czech Clinical Research Infrastructure Network, Brno, Czech Republic $1 https://orcid.org/0000000291902610
700    1_
$a Jancoriene, Ligita $u Institute of Clinical Medicine, Medical Faculty, Vilnius University, Vilnius, Lithuania $u Vilnius University Hospital Santaros klinikos, Medical Faculty, Vilnius University, Vilnius, Lithuania $1 https://orcid.org/0000000164886312
700    1_
$a Launay, Odile $u Institut National de la Santé et de la Recherche Médicale - France Recherche Nord & Sud Sida- HIV Hépatites Maladies Infectieuses Émergentes, Paris, France $u Assistance Publique Hopitaux de Paris, Université Paris Cité, Paris, France $1 https://orcid.org/0000000332427247
700    1_
$a Lundgren, Jens $u Centre of Excellence for Health, Immunity and Infections, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark $1 https://orcid.org/0000000189017850
700    1_
$a Mallon, Patrick $u Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin, Dublin, Ireland $1 https://orcid.org/0000000243376222
700    1_
$a Armeftis, Charis $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0009000780916711
700    1_
$a Marques, Laura $u Centro Hospitalar Universitário do Porto, Porto, Portugal $1 https://orcid.org/0000000264460319
700    1_
$a Naucler, Pontus $u Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden $u Department of Medicine, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden $1 https://orcid.org/0000000281852648
700    1_
$a Ochando, Jordi $u Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain $1 https://orcid.org/0000000170371681
700    1_
$a Tacconelli, Evelina $u Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, Verona, Italy $1 https://orcid.org/0000000320104977
700    1_
$a van Damme, Pierre $u VAXINFECTIO, Centre of Evaluation of Vaccination, Faculty of Medicine and Health Science, Universiteit Antwerpen, Antwerp, Belgium $1 https://orcid.org/0000000286421249
700    1_
$a Zaoutis, Theoklis $u Collaborative Center for Clinical Epidemiology and Outcomes Research, Athens, Greece $1 https://orcid.org/0000000301276562
700    1_
$a Hofstraat, Sanne $u University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands $1 https://orcid.org/0009000456722106
700    1_
$a Bruijning-Verhagen, Patricia $u University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands $1 https://orcid.org/0000000341059669
700    1_
$a Zeitlinger, Markus $u Medizinische Universität Wien, Vienna, Austria $1 https://orcid.org/0000000218733953
700    1_
$a Cornely, Oliver A $u Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u Clinical Trials Centre Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany $u German Centre for Infection Research, Partner Site Bonn-Cologne, Cologne, Germany $1 https://orcid.org/0000000195993137
700    1_
$a Pana, Zoi Dorothea $u School of Medicine, European University Cyprus, Nicosia, Cyprus $1 https://orcid.org/0000000258931081
773    0_
$w MED00208708 $t JMIR public health and surveillance $x 2369-2960 $g Roč. 9 (20230403), s. e44491
856    41
$u https://pubmed.ncbi.nlm.nih.gov/36878478 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20230718 $b ABA008
991    __
$a 20240206144417 $b ABA008
999    __
$a ok $b bmc $g 1963119 $s 1196769
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2023 $b 9 $c - $d e44491 $e 20230403 $i 2369-2960 $m JMIR public health and surveillance $n JMIR Public Health Surveill $x MED00208708
LZP    __
$a Pubmed-20230718

Najít záznam

Citační ukazatele

Možnosti archivace