• Je něco špatně v tomto záznamu ?

Degrade to survive: the intricate world of piroplasmid proteases

M. Florin-Christensen, D. Sojka, S. Ganzinelli, P. Šnebergerová, CE. Suarez, L. Schnittger

. 2023 ; 39 (7) : 532-546. [pub] 20230602

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc23010872

Piroplasmids of the genera Babesia, Theileria, and Cytauxzoon are tick-transmitted parasites with a high impact on animals and humans. They have complex life cycles in their definitive arthropod and intermediate vertebrate hosts involving numerous processes, including invasion of, and egress from, host cells, parasite growth, transformation, and migration. Like other parasitic protozoa, piroplasmids are equipped with different types of protease to fulfill many of such essential processes. Blockade of some key proteases, using inhibitors or antibodies, hinders piroplasmid growth, highlighting their potential usefulness in drug therapies and vaccine development. A better understanding of the functional significance of these enzymes will contribute to the development of improved control measures for the devastating animal and human diseases caused by these pathogens.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc23010872
003      
CZ-PrNML
005      
20230801132651.0
007      
ta
008      
230718s2023 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.pt.2023.04.010 $2 doi
035    __
$a (PubMed)37271664
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Florin-Christensen, Monica $u Instituto de Patobiología Veterinaria, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Castelar, Los Reseros y Nicolas Repetto s/n, Hurlingham 1686, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires C1033AAJ, Argentina. Electronic address: jacobsen.monica@inta.gob.ar
245    10
$a Degrade to survive: the intricate world of piroplasmid proteases / $c M. Florin-Christensen, D. Sojka, S. Ganzinelli, P. Šnebergerová, CE. Suarez, L. Schnittger
520    9_
$a Piroplasmids of the genera Babesia, Theileria, and Cytauxzoon are tick-transmitted parasites with a high impact on animals and humans. They have complex life cycles in their definitive arthropod and intermediate vertebrate hosts involving numerous processes, including invasion of, and egress from, host cells, parasite growth, transformation, and migration. Like other parasitic protozoa, piroplasmids are equipped with different types of protease to fulfill many of such essential processes. Blockade of some key proteases, using inhibitors or antibodies, hinders piroplasmid growth, highlighting their potential usefulness in drug therapies and vaccine development. A better understanding of the functional significance of these enzymes will contribute to the development of improved control measures for the devastating animal and human diseases caused by these pathogens.
650    _2
$a zvířata $7 D000818
650    _2
$a lidé $7 D006801
650    _2
$a proteasy $7 D010447
650    12
$a Babesia $x genetika $7 D001403
650    12
$a Piroplasmida $7 D016792
650    12
$a Theileria $7 D016794
650    12
$a klíšťata $x parazitologie $7 D013987
650    12
$a babezióza $x parazitologie $7 D001404
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Sojka, Daniel $u Institute of Parasitology, Biology Centre, Academy of Sciences of the Czech Republic, Branišovská 1160/31, CZ-37005 České Budějovice, Czech Republic
700    1_
$a Ganzinelli, Sabrina $u Instituto de Patobiología Veterinaria, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Castelar, Los Reseros y Nicolas Repetto s/n, Hurlingham 1686, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires C1033AAJ, Argentina
700    1_
$a Šnebergerová, Pavla $u Institute of Parasitology, Biology Centre, Academy of Sciences of the Czech Republic, Branišovská 1160/31, CZ-37005 České Budějovice, Czech Republic; Faculty of Science, University of South Bohemia, CZ-370 05 České Budějovice, Czech Republic
700    1_
$a Suarez, Carlos E $u Washington State University/Animal Disease Research Unit USDA, Pullman, WA, USA
700    1_
$a Schnittger, Leonhard $u Instituto de Patobiología Veterinaria, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Castelar, Los Reseros y Nicolas Repetto s/n, Hurlingham 1686, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires C1033AAJ, Argentina
773    0_
$w MED00006043 $t Trends in parasitology $x 1471-5007 $g Roč. 39, č. 7 (2023), s. 532-546
856    41
$u https://pubmed.ncbi.nlm.nih.gov/37271664 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20230718 $b ABA008
991    __
$a 20230801132647 $b ABA008
999    __
$a ok $b bmc $g 1963343 $s 1197137
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2023 $b 39 $c 7 $d 532-546 $e 20230602 $i 1471-5007 $m Trends in parasitology $n Trends Parasitol $x MED00006043
LZP    __
$a Pubmed-20230718
Zpět

Najít záznam

Citační ukazatele

Možnosti archivace