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Molecular Regulation of the CNS by Vitamin D
L. Máčová, R. Kancheva, M. Bičíková
Language English Country Czech Republic
Document type Review, Journal Article
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- MeSH
- Alzheimer Disease * MeSH
- Humans MeSH
- Nervous System Diseases * MeSH
- Parkinson Disease * MeSH
- Vitamin D therapeutic use MeSH
- Vitamins MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Vitamin D is a lipid-soluble vitamin that can be found in some foods. It is also produced endogenously (in the presence of ultraviolet light), transported through the blood to the targets organs and this is the reason to consider vitamin D as a hormone. It is known that vitamin D has genomic and non-genomic effects. This review is focused mainly on the vitamin D receptors, the importance of vitamin D as a neuromodulator, the role of vitamin D in the pathophysiology of devastating neurological disorders such as Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease and the benefit of vitamin D and its derivates in alleviating these disorders.
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