• Something wrong with this record ?

Impact of Mild Behavioral Impairment on Longitudinal Changes in Cognition

HJ. Rouse, Z. Ismail, R. Andel, VA. Molinari, JA. Schinka, BJ. Small

. 2024 ; 79 (1) : . [pub] 2024Jan01

Language English Country United States

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc24000167

BACKGROUND: To examine cross-sectional differences and longitudinal changes in cognitive performance based on the presence of mild behavioral impairment (MBI) among older adults who are cognitively healthy or have mild cognitive impairment (MCI). METHODS: Secondary data analysis of participants (n = 17 291) who were cognitively healthy (n = 11 771) or diagnosed with MCI (n = 5 520) from the National Alzheimer's Coordinating Center database. Overall, 24.7% of the sample met the criteria for MBI. Cognition was examined through a neuropsychological battery that assessed attention, episodic memory, executive function, language, visuospatial ability, and processing speed. RESULTS: Older adults with MBI, regardless of whether they were cognitively healthy or diagnosed with MCI, performed significantly worse at baseline on tasks for attention, episodic memory, executive function, language, and processing speed and exhibited greater longitudinal declines on tasks of attention, episodic memory, language, and processing speed. Cognitively healthy older adults with MBI performed significantly worse than those who were cognitively healthy without MBI on tasks of visuospatial ability at baseline and on tasks of processing speed across time. Older adults with MCI and MBI performed significantly worse than those with only MCI on executive function at baseline and visuospatial ability and processing speed tasks across time. CONCLUSIONS: This study found evidence that MBI is related to poorer cognitive performance cross-sectionally and longitudinally. Additionally, those with MBI and MCI performed worse across multiple tasks of cognition both cross-sectionally and across time. These results provide support for MBI being uniquely associated with different aspects of cognition.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24000167
003      
CZ-PrNML
005      
20240213093010.0
007      
ta
008      
240109s2024 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1093/gerona/glad098 $2 doi
035    __
$a (PubMed)37052173
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Rouse, Hillary J $u School of Aging Studies, University of South Florida, Tampa, Florida, USA $1 https://orcid.org/0000000195886462
245    10
$a Impact of Mild Behavioral Impairment on Longitudinal Changes in Cognition / $c HJ. Rouse, Z. Ismail, R. Andel, VA. Molinari, JA. Schinka, BJ. Small
520    9_
$a BACKGROUND: To examine cross-sectional differences and longitudinal changes in cognitive performance based on the presence of mild behavioral impairment (MBI) among older adults who are cognitively healthy or have mild cognitive impairment (MCI). METHODS: Secondary data analysis of participants (n = 17 291) who were cognitively healthy (n = 11 771) or diagnosed with MCI (n = 5 520) from the National Alzheimer's Coordinating Center database. Overall, 24.7% of the sample met the criteria for MBI. Cognition was examined through a neuropsychological battery that assessed attention, episodic memory, executive function, language, visuospatial ability, and processing speed. RESULTS: Older adults with MBI, regardless of whether they were cognitively healthy or diagnosed with MCI, performed significantly worse at baseline on tasks for attention, episodic memory, executive function, language, and processing speed and exhibited greater longitudinal declines on tasks of attention, episodic memory, language, and processing speed. Cognitively healthy older adults with MBI performed significantly worse than those who were cognitively healthy without MBI on tasks of visuospatial ability at baseline and on tasks of processing speed across time. Older adults with MCI and MBI performed significantly worse than those with only MCI on executive function at baseline and visuospatial ability and processing speed tasks across time. CONCLUSIONS: This study found evidence that MBI is related to poorer cognitive performance cross-sectionally and longitudinally. Additionally, those with MBI and MCI performed worse across multiple tasks of cognition both cross-sectionally and across time. These results provide support for MBI being uniquely associated with different aspects of cognition.
650    _2
$a lidé $7 D006801
650    _2
$a senioři $7 D000368
650    _2
$a průřezové studie $7 D003430
650    _2
$a kognice $7 D003071
650    12
$a kognitivní dysfunkce $7 D060825
650    _2
$a exekutivní funkce $7 D056344
650    12
$a epizodická paměť $7 D061212
650    _2
$a neuropsychologické testy $7 D009483
655    _2
$a časopisecké články $7 D016428
700    1_
$a Ismail, Zahinoor $u Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada $u Department of Psychiatry, Clinical Neurosciences, and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
700    1_
$a Andel, Ross $u Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA $u Department of Neurology, Charles University, Prague, Czech Republic
700    1_
$a Molinari, Victor A $u School of Aging Studies, University of South Florida, Tampa, Florida, USA
700    1_
$a Schinka, John A $u School of Aging Studies, University of South Florida, Tampa, Florida, USA
700    1_
$a Small, Brent J $u School of Aging Studies, University of South Florida, Tampa, Florida, USA $1 https://orcid.org/0000000274444689
773    0_
$w MED00003053 $t The journals of gerontology. Series A, Biological sciences and medical sciences $x 1758-535X $g Roč. 79, č. 1 (2024)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/37052173 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20240109 $b ABA008
991    __
$a 20240213093007 $b ABA008
999    __
$a ok $b bmc $g 2049075 $s 1209861
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 79 $c 1 $e 2024Jan01 $i 1758-535X $m The journals of gerontology. Series A, Biological sciences and medical sciences $n J Gerontol A Biol Sci Med Sci $x MED00003053
LZP    __
$a Pubmed-20240109

Find record

Citation metrics

Archiving options