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Je něco špatně v tomto záznamu ?
Retinal venular vessel diameters are smaller during ten days of bed rest
A. Saloň, GM. Çiftci, D. Zubac, B. Šimunič, R. Pišot, M. Narici, PM. Fredriksen, BN. Nkeh-Chungag, H. Sourij, O. Šerý, K. Schmid-Zalaudek, B. Steuber, P. De Boever, N. Goswami
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
Directory of Open Access Journals
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- MeSH
- arteria centralis retinae * diagnostické zobrazování MeSH
- fluoresceinová angiografie MeSH
- klid na lůžku škodlivé účinky MeSH
- lidé MeSH
- retinální cévy diagnostické zobrazování MeSH
- vena centralis retinae * diagnostické zobrazování MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Older individuals experience cardiovascular dysfunction during extended bedridden hospital or care home stays. Bed rest is also used as a model to simulate accelerated vascular deconditioning occurring during spaceflight. This study investigates changes in retinal microcirculation during a ten-day bed rest protocol. Ten healthy young males (22.9 ± 4.7 years; body mass index: 23.6 ± 2.5 kg·m-2) participated in a strictly controlled repeated-measures bed rest study lasting ten days. High-resolution images were obtained using a hand-held fundus camera at baseline, daily during the 10 days of bed rest, and 1 day after re-ambulation. Retinal vessel analysis was performed using a semi-automated software system to obtain metrics for retinal arteriolar and venular diameters, central retinal artery equivalent and central retinal vein equivalent, respectively. Data analysis employed a mixed linear model. At the end of the bed rest period, a significant decrease in retinal venular diameter was observed, indicated by a significantly lower central retinal vein equivalent (from 226.1 μm, CI 8.90, to 211.4 μm, CI 8.28, p = .026), while no significant changes in central retinal artery equivalent were noted. Prolonged bed rest confinement resulted in a significant (up to 6.5%) reduction in retinal venular diameter. These findings suggest that the changes in retinal venular diameter during bedrest may be attributed to plasma volume losses and reflect overall (cardio)-vascular deconditioning.
Centre for Environmental Sciences Hasselt University Hasselt Belgium
Department of Biomedical Sciences University of Padua Padua Italy
Department of Psychiatry University Hospital Münster Münster Germany
Institute for Kinesiology Research Science and Research Centre Koper Koper Slovenia
Integrative Health Alma Mater Europaea Maribor Maribor Slovenia
Citace poskytuje Crossref.org
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