Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

The glymphatic system in migraine and other headaches

MG. Vittorini, A. Sahin, A. Trojan, S. Yusifli, T. Alashvili, GV. Bonifácio, K. Paposhvili, V. Tischler, C. Lampl, S. Sacco, School of Advanced Studies of the European Headache Federation (EHF-SAS)

. 2024 ; 25 (1) : 34. [pub] 20240311

Language English Country England, Great Britain

Document type Journal Article, Review

Persistent link   https://www.medvik.cz/link/bmc24006750

Glymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It is made of a network of perivascular spaces, filled in cerebrospinal and interstitial fluid, encompassing penetrating and pial vessels and communicating with the subarachnoid space. It is separated from vessels by the blood brain barrier and from brain tissue by the endfeet of the astrocytes rich in aquaporin 4, a membrane protein which controls the water flow along the perivascular space. Animal models and magnetic resonance (MR) studies allowed to characterize the glymphatic system function and determine how its impairment could lead to numerous neurological disorders (e.g. Alzheimer's disease, stroke, sleep disturbances, migraine, idiopathic normal pressure hydrocephalus). This review aims to summarize the role of the glymphatic system in the pathophysiology of migraine in order to provide new ways of approaching to this disease and to its therapy.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24006750
003      
CZ-PrNML
005      
20240423155459.0
007      
ta
008      
240412s2024 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1186/s10194-024-01741-2 $2 doi
035    __
$a (PubMed)38462633
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Vittorini, Maria Grazia $u Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
245    14
$a The glymphatic system in migraine and other headaches / $c MG. Vittorini, A. Sahin, A. Trojan, S. Yusifli, T. Alashvili, GV. Bonifácio, K. Paposhvili, V. Tischler, C. Lampl, S. Sacco, School of Advanced Studies of the European Headache Federation (EHF-SAS)
520    9_
$a Glymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It is made of a network of perivascular spaces, filled in cerebrospinal and interstitial fluid, encompassing penetrating and pial vessels and communicating with the subarachnoid space. It is separated from vessels by the blood brain barrier and from brain tissue by the endfeet of the astrocytes rich in aquaporin 4, a membrane protein which controls the water flow along the perivascular space. Animal models and magnetic resonance (MR) studies allowed to characterize the glymphatic system function and determine how its impairment could lead to numerous neurological disorders (e.g. Alzheimer's disease, stroke, sleep disturbances, migraine, idiopathic normal pressure hydrocephalus). This review aims to summarize the role of the glymphatic system in the pathophysiology of migraine in order to provide new ways of approaching to this disease and to its therapy.
650    _2
$a zvířata $7 D000818
650    12
$a glymfatický systém $x diagnostické zobrazování $x metabolismus $7 D000077502
650    12
$a migréna $x diagnostické zobrazování $x metabolismus $7 D008881
650    _2
$a hematoencefalická bariéra $x metabolismus $7 D001812
650    12
$a nemoci nervového systému $x metabolismus $7 D009422
650    _2
$a bolesti hlavy $x metabolismus $7 D006261
650    _2
$a mozek $x diagnostické zobrazování $x metabolismus $7 D001921
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Sahin, Aysenur $u Faculty of Medicine-Acibadem Mehmet, Ali Aydinlar University, Istanbul, Turkey
700    1_
$a Trojan, Antonin $u Department of Neurology, Strakonice Hospital, Strakonice, Czechia
700    1_
$a Yusifli, Sevil $u Faculty of Medicine-Istanbul University, Istanbul, Turkey
700    1_
$a Alashvili, Tamta $u Department of Internal Medicine, New Vision University Hospital, Tbilisi, Georgia
700    1_
$a Bonifácio, Gonçalo V $u Department of Neurology, Hospital de São Bernardo, Setúbal, Portugal
700    1_
$a Paposhvili, Ketevan $u Department of Neurology, Tbilisi State Medical University, Tbilisi, Georgia
700    1_
$a Tischler, Viktoria $u Department of Neurology, Konventhospital Barmherzige Brüder Linz, Linz, Austria
700    1_
$a Lampl, Christian $u Department of Neurology, Konventhospital Barmherzige Brüder Linz, Linz, Austria. christian.lampl@bblinz.at
700    1_
$a Sacco, Simona $u Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
710    2_
$a School of Advanced Studies of the European Headache Federation (EHF-SAS)
773    0_
$w MED00005758 $t The Journal of headaches and pain $x 1129-2377 $g Roč. 25, č. 1 (2024), s. 34
856    41
$u https://pubmed.ncbi.nlm.nih.gov/38462633 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20240412 $b ABA008
991    __
$a 20240423155455 $b ABA008
999    __
$a ok $b bmc $g 2081003 $s 1216517
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 25 $c 1 $d 34 $e 20240311 $i 1129-2377 $m The Journal of headaches and pain $n J Headache Pain $x MED00005758
LZP    __
$a Pubmed-20240412

Find record

Citation metrics

Archiving options