• Je něco špatně v tomto záznamu ?

Detecting horizontal gene transfer among microbiota: an innovative pipeline for identifying co-shared genes within the mobilome through advanced comparative analysis

J. Schwarzerova, M. Zeman, V. Babak, K. Jureckova, M. Nykrynova, M. Varga, W. Weckwerth, M. Dolejska, V. Provaznik, I. Rychlik, D. Cejkova

. 2024 ; 12 (1) : e0196423. [pub] 20231215

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc24007602

Grantová podpora
GA22-16786S Czech Science Foundation
206/2023/FVHE Internal Grant Agency of the University of Veterinary Sciences Brno

Horizontal gene transfer (HGT) is a key driver in the evolution of bacterial genomes. The acquisition of genes mediated by HGT may enable bacteria to adapt to ever-changing environmental conditions. Long-term application of antibiotics in intensive agriculture is associated with the dissemination of antibiotic resistance genes among bacteria with the consequences causing public health concern. Commensal farm-animal-associated gut microbiota are considered the reservoir of the resistance genes. Therefore, in this study, we identified known and not-yet characterized mobilized genes originating from chicken and porcine fecal samples using our innovative pipeline followed by network analysis to provide appropriate visualization to support proper interpretation.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24007602
003      
CZ-PrNML
005      
20240423160122.0
007      
ta
008      
240412s2024 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1128/spectrum.01964-23 $2 doi
035    __
$a (PubMed)38099617
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Schwarzerova, Jana $u Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic $u Molecular Systems Biology (MOSYS), Department of Functional and Evolutionary Ecology, University of Vienna , Vienna, Austria
245    10
$a Detecting horizontal gene transfer among microbiota: an innovative pipeline for identifying co-shared genes within the mobilome through advanced comparative analysis / $c J. Schwarzerova, M. Zeman, V. Babak, K. Jureckova, M. Nykrynova, M. Varga, W. Weckwerth, M. Dolejska, V. Provaznik, I. Rychlik, D. Cejkova
520    9_
$a Horizontal gene transfer (HGT) is a key driver in the evolution of bacterial genomes. The acquisition of genes mediated by HGT may enable bacteria to adapt to ever-changing environmental conditions. Long-term application of antibiotics in intensive agriculture is associated with the dissemination of antibiotic resistance genes among bacteria with the consequences causing public health concern. Commensal farm-animal-associated gut microbiota are considered the reservoir of the resistance genes. Therefore, in this study, we identified known and not-yet characterized mobilized genes originating from chicken and porcine fecal samples using our innovative pipeline followed by network analysis to provide appropriate visualization to support proper interpretation.
650    _2
$a zvířata $7 D000818
650    _2
$a prasata $7 D013552
650    12
$a přenos genů horizontální $7 D022761
650    12
$a mikrobiota $7 D064307
650    _2
$a genom bakteriální $7 D016680
650    _2
$a antibakteriální látky $7 D000900
650    _2
$a Bacteria $x genetika $7 D001419
650    _2
$a bakteriální geny $7 D005798
655    _2
$a časopisecké články $7 D016428
700    1_
$a Zeman, Michal $u Veterinary Research Institute , Brno, Czech Republic
700    1_
$a Babak, Vladimir $u Veterinary Research Institute , Brno, Czech Republic
700    1_
$a Jureckova, Katerina $u Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic
700    1_
$a Nykrynova, Marketa $u Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic
700    1_
$a Varga, Margaret $u Department of Biology, University of Oxford , Oxford, United Kingdom
700    1_
$a Weckwerth, Wolfram $u Molecular Systems Biology (MOSYS), Department of Functional and Evolutionary Ecology, University of Vienna , Vienna, Austria $u Vienna Metabolomics Center (VIME), University of Vienna , Vienna, Austria
700    1_
$a Dolejska, Monika $u Central European Institute of Technology, University of Veterinary Sciences Brno , Brno, Czech Republic $u Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary Sciences Brno , Brno, Czech Republic $u Department of Clinical Microbiology and Immunology, Institute of Laboratory Medicine, The University Hospital Brno , Brno, Czech Republic $u Biomedical Center, Faculty of Medicine, Charles University , Pilsen, Czech Republic
700    1_
$a Provaznik, Valentine $u Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic $u Department of Physiology, Faculty of Medicine, Masaryk University , Brno, Czech Republic
700    1_
$a Rychlik, Ivan $u Veterinary Research Institute , Brno, Czech Republic
700    1_
$a Cejkova, Darina $u Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic $1 https://orcid.org/0000000269896330
773    0_
$w MED00209157 $t Microbiology spectrum $x 2165-0497 $g Roč. 12, č. 1 (2024), s. e0196423
856    41
$u https://pubmed.ncbi.nlm.nih.gov/38099617 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20240412 $b ABA008
991    __
$a 20240423160118 $b ABA008
999    __
$a ok $b bmc $g 2081540 $s 1217369
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 12 $c 1 $d e0196423 $e 20231215 $i 2165-0497 $m Microbiology spectrum $n Microbiol Spectr $x MED00209157
GRA    __
$a GA22-16786S $p Czech Science Foundation
GRA    __
$a 206/2023/FVHE $p Internal Grant Agency of the University of Veterinary Sciences Brno
LZP    __
$a Pubmed-20240412

Najít záznam

Citační ukazatele

    Možnosti archivace