-
Je něco špatně v tomto záznamu ?
A severe case of pemphigoid gestationis persisting after labour - case report and review of the literature
H. Herman, P. Krepelka, AT. Faridova, K. Trojanova, J. Hanacek, B. Jaluvkova, J. Feyereisl, S. Gkalpakiotis
Jazyk angličtina Země Česko
Typ dokumentu kazuistiky, časopisecké články, přehledy
NLK
Directory of Open Access Journals
od 2001
Free Medical Journals
od 1998
Medline Complete (EBSCOhost)
od 2007-06-01
ROAD: Directory of Open Access Scholarly Resources
od 2001
PubMed
36919665
DOI
10.5507/bp.2023.010
Knihovny.cz E-zdroje
- MeSH
- císařský řez MeSH
- cyklosporin terapeutické užití MeSH
- dospělí MeSH
- lidé MeSH
- novorozenec MeSH
- pemphigoid gestationis * farmakoterapie diagnóza MeSH
- předčasný odtok plodové vody MeSH
- těhotenství MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- přehledy MeSH
BACKGROUND AND AIM: Pemphigoid gestationis (PG) is a rare skin disease of pregnancy. Given its incidence in pregnant women, physicians and especially obstetricians may not encounter this diagnosis in their entire career. We find this to be a major problem and there is an obligation to report it in as much detail as possible along with recommended treatments with proven efficacy. CASE REPORT: We describe the case of a 27 year old patient who was referred to the dermatology department with severe dissemination of blisters in the 9th week of pregnancy. She was diagnosed with pemphigoid gestationis in her first pregnancy. High doses of corticosteroids were initiated but due to inadequate effect cyclosporine was added. The pregnancy was complicated with gestational diabetes. The patient gave birth in her 33rd week by caesarian section due to premature rupture of the membrane. Vesicles were seen on the newborn immediately after birth which diminished spontaneously over 2 weeks. Blisters were still seen on the patient 1 month after labor even with the combination of systemic corticosteroids with cyclosporine. CONCLUSION: PG is a rare dermatosis of pregnancy. The course of the disease can be severe, necessitating systemic therapy. As described in this patient, systemic corticosteroids may not be sufficient and adding another immunosuppressive treatment may be needed. If pemphigoid gestationis has occurred during a previous pregnancy it is advised to reconsider another pregnancy.
3rd Faculty of Medicine Charles University Prague Czech Republic
Department of Dermatovenereology University Hospital of Kralovske Vinohrady Prague Czech republic
Institute for the Care of Mother and Child Prague Czech Republic
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc24017563
- 003
- CZ-PrNML
- 005
- 20250507135842.0
- 007
- ta
- 008
- 241004s2024 xr a f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.5507/bp.2023.010 $2 doi
- 035 __
- $a (PubMed)36919665
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Heřman, Hynek, $d 1972- $u Institute for the Care of Mother and Child, Prague, Czech Republic $u Third Faculty of Medicine, Charles University, Prague, Czech Republic $7 xx0073991
- 245 12
- $a A severe case of pemphigoid gestationis persisting after labour - case report and review of the literature / $c H. Herman, P. Krepelka, AT. Faridova, K. Trojanova, J. Hanacek, B. Jaluvkova, J. Feyereisl, S. Gkalpakiotis
- 520 9_
- $a BACKGROUND AND AIM: Pemphigoid gestationis (PG) is a rare skin disease of pregnancy. Given its incidence in pregnant women, physicians and especially obstetricians may not encounter this diagnosis in their entire career. We find this to be a major problem and there is an obligation to report it in as much detail as possible along with recommended treatments with proven efficacy. CASE REPORT: We describe the case of a 27 year old patient who was referred to the dermatology department with severe dissemination of blisters in the 9th week of pregnancy. She was diagnosed with pemphigoid gestationis in her first pregnancy. High doses of corticosteroids were initiated but due to inadequate effect cyclosporine was added. The pregnancy was complicated with gestational diabetes. The patient gave birth in her 33rd week by caesarian section due to premature rupture of the membrane. Vesicles were seen on the newborn immediately after birth which diminished spontaneously over 2 weeks. Blisters were still seen on the patient 1 month after labor even with the combination of systemic corticosteroids with cyclosporine. CONCLUSION: PG is a rare dermatosis of pregnancy. The course of the disease can be severe, necessitating systemic therapy. As described in this patient, systemic corticosteroids may not be sufficient and adding another immunosuppressive treatment may be needed. If pemphigoid gestationis has occurred during a previous pregnancy it is advised to reconsider another pregnancy.
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a těhotenství $7 D011247
- 650 12
- $a pemphigoid gestationis $x farmakoterapie $x diagnóza $7 D006559
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a novorozenec $7 D007231
- 650 _2
- $a cyklosporin $x terapeutické užití $7 D016572
- 650 _2
- $a císařský řez $7 D002585
- 650 _2
- $a předčasný odtok plodové vody $7 D005322
- 655 _2
- $a kazuistiky $7 D002363
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Křepelka, Petr $u Institute for the Care of Mother and Child, Prague, Czech Republic $u Third Faculty of Medicine, Charles University, Prague, Czech Republic $7 osa2013777769
- 700 1_
- $a Tefr Faridová, Adéla $u Institute for the Care of Mother and Child, Prague, Czech Republic $7 xx0239484
- 700 1_
- $a Trojanová, Klára $u Institute for the Care of Mother and Child, Prague, Czech Republic $7 xx0283354
- 700 1_
- $a Hanáček, Jiří $u Institute for the Care of Mother and Child, Prague, Czech Republic $u Third Faculty of Medicine, Charles University, Prague, Czech Republic $7 xx0061366
- 700 1_
- $a Jalůvková, Barbora $u Rudolf and Stefanie Hospital, Benesov u Prahy, Czech Republic $7 xx0283348
- 700 1_
- $a Feyereisl, Jaroslav, $d 1954- $u Institute for the Care of Mother and Child, Prague, Czech Republic $u Third Faculty of Medicine, Charles University, Prague, Czech Republic $7 nlk20010093266
- 700 1_
- $a Gkalpakiotis, Spyridon $u Third Faculty of Medicine, Charles University, Prague, Czech Republic $u Department of Dermatovenereology, University Hospital of Kralovske Vinohrady, Prague, Czech republic $7 xx0094696
- 773 0_
- $w MED00012606 $t Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia $x 1804-7521 $g Roč. 168, č. 3 (2024), s. 271-275
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/36919665 $y Pubmed
- 910 __
- $a ABA008 $b A 1502 $c 958 $y p $z 0
- 990 __
- $a 20241004 $b ABA008
- 991 __
- $a 20250507135839 $b ABA008
- 999 __
- $a ok $b bmc $g 2316483 $s 1229513
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2024 $b 168 $c 3 $d 271-275 $e 20230314 $i 1804-7521 $m Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia $n Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub $x MED00012606
- LZP __
- $b NLK124 $a Pubmed-20241004