Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Safety and efficacy of simple training protocol in patients after mild traumatic brain injury

M. Martinikova, R. Ruzinak, P. Hnilicova, M. Bittsansky, M. Grendar, L. Babalova, P. Skacik, E. Kantorova, V. Nosal, M. Turcanova Koprusakova, J. Sivak, J. Sivakova, Z. Biringerova, B. Kolarovszki, K. Zelenak, E. Kurca, S. Sivak

. 2024 ; 168 (4) : 295-303. [pub] 20230504

Jazyk angličtina Země Česko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc24022793

AIMS: Mild Traumatic Brain Injury (mTBI) is the most common type of craniocerebral injury. Proper management appears to be a key factor in preventing post-concussion syndrome. The aim of this prospective study was to evaluate the effect and safety of selected training protocol in patients after mTBI. METHODS: This was a prospective study that included 25 patients with mTBI and 25 matched healthy controls. Assessments were performed in two sessions and included a post-concussion symptoms questionnaire, battery of neurocognitive tests, and magnetic resonance with tractography. Participants were divided into two groups: a passive subgroup with no specific recommendations and an active subgroup with simple physical and cognitive training. RESULTS: The training program with slightly higher initial physical and cognitive loads was well tolerated and was harmless according to the noninferiority test. The tractography showed overall temporal posttraumatic changes in the brain. The predictive model was able to distinguish between patients and controls in the first (AUC=0.807) and second (AUC=0.652) sessions. In general, tractography had an overall predictive dominance of measures. CONCLUSION: The results from our study objectively point to the safety of our chosen training protocol, simultaneously with the signs of slight benefits in specific cognitive domains. The study also showed the capability of machine learning and predictive models in mTBI patient recognition.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24022793
003      
CZ-PrNML
005      
20250528102522.0
007      
ta
008      
241205s2024 xr d f 000 0|eng||
009      
AR
024    7_
$a 10.5507/bp.2023.013 $2 doi
035    __
$a (PubMed)37157859
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Martiníková, Martina $u Second Department of Neurology, F. D. Roosevelt Faculty Hospital, Slovak Medical University, Banska Bystrica, Slovak Republic $7 xx0269032
245    10
$a Safety and efficacy of simple training protocol in patients after mild traumatic brain injury / $c M. Martinikova, R. Ruzinak, P. Hnilicova, M. Bittsansky, M. Grendar, L. Babalova, P. Skacik, E. Kantorova, V. Nosal, M. Turcanova Koprusakova, J. Sivak, J. Sivakova, Z. Biringerova, B. Kolarovszki, K. Zelenak, E. Kurca, S. Sivak
520    9_
$a AIMS: Mild Traumatic Brain Injury (mTBI) is the most common type of craniocerebral injury. Proper management appears to be a key factor in preventing post-concussion syndrome. The aim of this prospective study was to evaluate the effect and safety of selected training protocol in patients after mTBI. METHODS: This was a prospective study that included 25 patients with mTBI and 25 matched healthy controls. Assessments were performed in two sessions and included a post-concussion symptoms questionnaire, battery of neurocognitive tests, and magnetic resonance with tractography. Participants were divided into two groups: a passive subgroup with no specific recommendations and an active subgroup with simple physical and cognitive training. RESULTS: The training program with slightly higher initial physical and cognitive loads was well tolerated and was harmless according to the noninferiority test. The tractography showed overall temporal posttraumatic changes in the brain. The predictive model was able to distinguish between patients and controls in the first (AUC=0.807) and second (AUC=0.652) sessions. In general, tractography had an overall predictive dominance of measures. CONCLUSION: The results from our study objectively point to the safety of our chosen training protocol, simultaneously with the signs of slight benefits in specific cognitive domains. The study also showed the capability of machine learning and predictive models in mTBI patient recognition.
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a ženské pohlaví $7 D005260
650    12
$a komoce mozku $7 D001924
650    _2
$a prospektivní studie $7 D011446
650    _2
$a dospělí $7 D000328
650    12
$a postkomoční syndrom $7 D038223
650    _2
$a neuropsychologické testy $7 D009483
650    _2
$a mladý dospělý $7 D055815
650    _2
$a lidé středního věku $7 D008875
650    _2
$a studie případů a kontrol $7 D016022
650    _2
$a magnetická rezonanční tomografie $7 D008279
650    _2
$a zobrazování difuzních tenzorů $7 D056324
655    _2
$a časopisecké články $7 D016428
700    1_
$a Ružinák, R. $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0269031
700    1_
$a Hnilicová, Petra $u Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0253349
700    1_
$a Bittšanský, Michal $u Department of Medical Biochemistry, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0195465
700    1_
$a Grendár, Marián, $d 1969- $u Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0242991
700    1_
$a Babálová, Lucia $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0257232
700    1_
$a Skáčik, Pavol $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 _AN119811
700    1_
$a Kantorová, Ema $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0100579
700    1_
$a Nosáľ, Vladimír, $d 1973- $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0079042
700    1_
$a Turčanová Koprušáková, Monika $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0107010
700    1_
$a Sivák, Jozef $u Department of Radiology, The Central Slovak Institute for Cardiovascular Diseases in Banska Bystrica, Banska Bystrica, Slovak Republic $u Department of Radiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic $7 xx0332240
700    1_
$a Siváková, Jana, $d 1985- $u Clinic of Gynecology and Obstetrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0269907
700    1_
$a Biringerová, Zuzana $u Medical Education Support Center, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0194079
700    1_
$a Kolarovszki, Branislav $u Clinic of Neurosurgery, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0107843
700    1_
$a Zeleňák, Kamil $u Clinic of Radiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0231390
700    1_
$a Kurča, Egon, $d 1964- $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 nlk20050162662
700    1_
$a Sivák, Štefan $u Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic $7 xx0136791
773    0_
$w MED00012606 $t Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia $x 1804-7521 $g Roč. 168, č. 4 (2024), s. 295-303
856    41
$u https://pubmed.ncbi.nlm.nih.gov/37157859 $y Pubmed
910    __
$a ABA008 $b A 1502 $c 958 $y p $z 0
990    __
$a 20241205 $b ABA008
991    __
$a 20250528102520 $b ABA008
999    __
$a ok $b bmc $g 2324818 $s 1234798
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 168 $c 4 $d 295-303 $e 20230504 $i 1804-7521 $m Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia $n Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub $x MED00012606
LZP    __
$b NLK124 $a Pubmed-20241205
Zpět

Najít záznam

Citační ukazatele

Možnosti archivace