Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Ablation of Supraventricular Arrhythmias With as Low as Reasonably Achievable X-Ray exposure (AALARA): Results of Prospective, Observational, Multicenter, Multinational, Open-Label Registry Study on Real World Data Using Routine Ensite 3D Mapping During SVT Ablation

M. Amin, A. Abdrakhmanov, E. Kropotkin, V. Traykov, Z. Salló, L. Gellér, F. Lorgat, O. Sapelnikov, O. Toman, K. Al-Muti, M. Aljaabari, A. Bystriansky, L. Környei, N. Mujović, S. Simons, N. Szegedi

. 2024 ; 47 (11) : 1441-1448. [pub] 20240927

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, multicentrická studie, pozorovací studie, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc25003630

Grantová podpora
Abbott Medical

INTRODUCTION: The reduction of fluoroscopic exposure during catheter ablation of supraventricular arrhythmias is widely adopted by experienced electrophysiology physicians with a relatively short learning curve and is becoming the standard of care in many parts of the world. While observational studies in the United States and some parts of Western Europe have evaluated the minimal fluoroscopic approach, there are scarce real-world data for this technique and the generalizability of outcomes in other economic regions. METHOD: The AALARA study is a prospective, observational, multicenter, and multinational open-label study. Patients were recruited from 13 countries across Central Eastern Europe, North and South Africa, the Middle East, and the CIS (Commonwealth of Independent States), with different levels of operator expertise using minimal fluoroscopic exposure techniques. Data on radiation exposure, procedural success, complications, recurrence, and quality of life changes were collected and analyzed. RESULT: A total of 680 patients were enrolled and followed for 6 months. The majority were ablation naïve with the commonest arrhythmia ablated being typical AVNRT (58%) followed by Atrial Flutter (23%). Zero fluoroscopy exposure was observed in almost 90% of the cases. Fluoroscopy was most commonly used during the ablation phase of the procedure. We observed a high acute success rate (99%), a low complication rate (0.4%), and a 6-month recurrence rate of 3.8%. There was a significant improvement in the patient's symptoms and quality of life as measured by patient global assessment. CONCLUSION: The routine use of a 3D mapping system during right-sided ablation was associated with low radiation exposure and associated with high acute success rate, low complications, and recurrence rate along with significant improvement in quality of life. The data confirm the reproducibility of this approach in real-world settings across different healthcare systems, and operator experience supporting this approach to minimize radiation exposure without compromising efficacy and safety. TRIAL REGISTRATION: NCT04716270.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc25003630
003      
CZ-PrNML
005      
20250206104452.0
007      
ta
008      
250121s2024 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1111/pace.15075 $2 doi
035    __
$a (PubMed)39331462
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Amin, Mohammad $u Department of Cardiac Electrophysiology, Mohammed Bin Khalifa Bin Salman Al Khalifa Specialist Cardiac Centre, Awali, Bahrain $1 https://orcid.org/0000000222072967
245    10
$a Ablation of Supraventricular Arrhythmias With as Low as Reasonably Achievable X-Ray exposure (AALARA): Results of Prospective, Observational, Multicenter, Multinational, Open-Label Registry Study on Real World Data Using Routine Ensite 3D Mapping During SVT Ablation / $c M. Amin, A. Abdrakhmanov, E. Kropotkin, V. Traykov, Z. Salló, L. Gellér, F. Lorgat, O. Sapelnikov, O. Toman, K. Al-Muti, M. Aljaabari, A. Bystriansky, L. Környei, N. Mujović, S. Simons, N. Szegedi
520    9_
$a INTRODUCTION: The reduction of fluoroscopic exposure during catheter ablation of supraventricular arrhythmias is widely adopted by experienced electrophysiology physicians with a relatively short learning curve and is becoming the standard of care in many parts of the world. While observational studies in the United States and some parts of Western Europe have evaluated the minimal fluoroscopic approach, there are scarce real-world data for this technique and the generalizability of outcomes in other economic regions. METHOD: The AALARA study is a prospective, observational, multicenter, and multinational open-label study. Patients were recruited from 13 countries across Central Eastern Europe, North and South Africa, the Middle East, and the CIS (Commonwealth of Independent States), with different levels of operator expertise using minimal fluoroscopic exposure techniques. Data on radiation exposure, procedural success, complications, recurrence, and quality of life changes were collected and analyzed. RESULT: A total of 680 patients were enrolled and followed for 6 months. The majority were ablation naïve with the commonest arrhythmia ablated being typical AVNRT (58%) followed by Atrial Flutter (23%). Zero fluoroscopy exposure was observed in almost 90% of the cases. Fluoroscopy was most commonly used during the ablation phase of the procedure. We observed a high acute success rate (99%), a low complication rate (0.4%), and a 6-month recurrence rate of 3.8%. There was a significant improvement in the patient's symptoms and quality of life as measured by patient global assessment. CONCLUSION: The routine use of a 3D mapping system during right-sided ablation was associated with low radiation exposure and associated with high acute success rate, low complications, and recurrence rate along with significant improvement in quality of life. The data confirm the reproducibility of this approach in real-world settings across different healthcare systems, and operator experience supporting this approach to minimize radiation exposure without compromising efficacy and safety. TRIAL REGISTRATION: NCT04716270.
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a prospektivní studie $7 D011446
650    12
$a katetrizační ablace $x metody $7 D017115
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé středního věku $7 D008875
650    _2
$a fluoroskopie $7 D005471
650    12
$a radiační expozice $7 D000069079
650    _2
$a registrace $7 D012042
650    _2
$a zobrazování trojrozměrné $7 D021621
650    _2
$a supraventrikulární tachykardie $x chirurgie $7 D013617
650    _2
$a kvalita života $7 D011788
651    _2
$a Evropa $7 D005060
655    _2
$a časopisecké články $7 D016428
655    _2
$a multicentrická studie $7 D016448
655    _2
$a pozorovací studie $7 D064888
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Abdrakhmanov, Ayan $u Department of Cardiology, National Research Cardiac Surgery Center, NPJSC, Nur-Sultan, Kazakhstan $1 https://orcid.org/0000000163155016
700    1_
$a Kropotkin, Evgeniy $u Department of Cardiology, Federal Center for Cardiovascular Surgery, Krasnoyarsk Region, Russian Federation
700    1_
$a Traykov, Vasil $u Department of Cardiology, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria
700    1_
$a Salló, Zoltán $u Department of Cardiology, Semmelweis University Heart and Vascular Centre, Budapest, Hungary
700    1_
$a Gellér, László $u Department of Cardiology, Semmelweis University Heart and Vascular Centre, Budapest, Hungary $1 https://orcid.org/0000000168026360
700    1_
$a Lorgat, Faizel $u Department of Cardiology, Christian Barnard Memorial Hospital, Cape Town, South Africa
700    1_
$a Sapelnikov, Oleg $u Department of Cardiology, Institute of Clinical Cardiology, Moscow, Russian Federation
700    1_
$a Toman, Ondrej $u Department of Cardiology, University Hospital Brno, Brno-Bohunice, Czech Republic
700    1_
$a Al-Muti, Khalid $u Department of Cardiology, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE
700    1_
$a Aljaabari, Mohamed $u Department of Cardiology, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE
700    1_
$a Bystriansky, Adrian $u Department of Cardiology, Central Slovak Institute of Heart and Vascular Diseases, Banská Bystrica, Slovakia
700    1_
$a Környei, László $u Department of Cardiology, Gottsegen György National Cardiovascular Institute, Budapest, Hungary $1 https://orcid.org/0000000170126133
700    1_
$a Mujović, Nebojša $u Department of Cardiology, University Clinical Centre of Serbia, Belgrade, Serbia
700    1_
$a Simons, Stefanie $u CRO RQM+ (Germany) GmbH, Hamm, Germany
700    1_
$a Szegedi, Nándor $u Department of Cardiology, Semmelweis University Heart and Vascular Centre, Budapest, Hungary $1 https://orcid.org/000000015670745X
773    0_
$w MED00003671 $t Pacing and clinical electrophysiology $x 1540-8159 $g Roč. 47, č. 11 (2024), s. 1441-1448
856    41
$u https://pubmed.ncbi.nlm.nih.gov/39331462 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20250121 $b ABA008
991    __
$a 20250206104447 $b ABA008
999    __
$a ok $b bmc $g 2263403 $s 1239637
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 47 $c 11 $d 1441-1448 $e 20240927 $i 1540-8159 $m Pacing and clinical electrophysiology $n Pacing Clin Electrophysiol $x MED00003671
GRA    __
$p Abbott Medical
LZP    __
$a Pubmed-20250121

Najít záznam

Citační ukazatele

Možnosti archivace