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Bipolar radiofrequency ablation of refractory ventricular arrhythmias: results from a multicentre network
P. Futyma, A. Sultan, Ł. Zarębski, G. Imnadze, V. Maslova, S. Bordignon, M. Kousta, S. Knecht, N. Pavlović, P. Peichl, E. Lian, T. Kueffer, D. Scherr, M. Pfeffer, P. Moskal, G. Cismaru, B. Antolič, P. Wałek, S. Chen, M. Martinek, G. Kollias, M....
Language English Country England, Great Britain
Document type Journal Article, Multicenter Study
Grant support
European Heart Rhythm Association Scientific Initiatives Committee
EHRA-SIC
NLK
Free Medical Journals
from 1999 to 1 year ago
PubMed Central
from 2008
Open Access Digital Library
from 1999-01-01
Medline Complete (EBSCOhost)
from 1999-01-01
Oxford Journals Open Access Collection
from 1999-01-01
- MeSH
- Catheter Ablation * methods MeSH
- Tachycardia, Ventricular * surgery physiopathology MeSH
- Ventricular Premature Complexes * surgery physiopathology diagnosis MeSH
- Middle Aged MeSH
- Humans MeSH
- Recurrence * MeSH
- Registries * MeSH
- Aged MeSH
- Feasibility Studies MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Geographicals
- Europe MeSH
AIMS: Advanced ablation strategies are needed to treat ventricular tachycardia (VT) and premature ventricular complexes (PVC) refractory to standard unipolar radiofrequency ablation (Uni-RFA). Bipolar radiofrequency catheter ablation (Bi-RFA) has emerged as a treatment option for refractory VT and PVC. Multicentre registry data on the use of Bi-RFA in the setting of refractory VT and PVC are lacking. The aim of this Bi-RFA registry is to determine its real-world safety, feasibility, and efficacy in patients with refractory VT/PVC. METHODS AND RESULTS: Consecutive patients undergoing Bi-RFA at 16 European centres for recurring VT/PVC after at least one standard Uni-RFA were included. Second ablation catheter was used instead of a dispersive patch and was positioned at the opposite site of the ablation target. Between March 2021 and August 2024, 91 patients underwent 94 Bi-RFA procedures (74 males, age 62 ± 13, and prior Uni-RFA range 1-8). Indications were recurrence of PVC (n = 56), VT (n = 20), electrical storm (n = 13), or PVC-triggered ventricular fibrillation (n = 2). Procedural time was 160 ± 73 min, Bi-RFA time 426 ± 286 s, and mean Uni-RFA time 819 ± 697 s. Elimination of clinical VT/PVC was achieved in 67 (74%) patients and suppression of VT/PVC in a further 10 (11%) patients. In the remaining 14 patients (15%), no effect on VT/PVC was observed. Three major complications occurred: coronary artery occlusion, atrioventricular block, and arteriovenous fistula. Follow-up lasted 7 ± 8 months. Nineteen patients (61%) remained VT free. ≥80% PVC burden reduction was achieved in 45 (78%). CONCLUSION: These real-world registry data indicate that Bi-RFA appears safe, is feasible, and is effective in the majority of patients with VT/PVC.
1st Clinic of Cardiology and Electrotherapy Swietokrzyskie Cardiology Centre Kielce Poland
Cardioangiologisches Centrum Bethanien Department Kardiologie Markus Krankenhaus Frankfurt Germany
Cardiovascular Research Institute Basel University Hospital Basel Basel Switzerland
Clinical Electrophysiology Hospital of the University of Pennsylvania Philadelphia Pennsylvania USA
Collegium Medicum Jan Kochanowski University Kielce Poland
Department for Cardiovascular Medicine University Hospital Dubrava Zagreb Croatia
Department of Cardiology Inselspital Bern University Hospital University of Bern Bern Switzerland
Department of Cardiology Institute for Clinical and Experimental Medicine Prague Czech Republic
Department of Cardiology University Hospital Basel Basel Switzerland
Department of Cardiology University Medical Centre of Ljubljana Ljubljana Slovenia
Department of Internal Medicine 3 Kiel Germany
Division of Cardiology Department of Medicine Medical University of Graz Graz Austria
Heart Center Department of Electrophysiology University Hospital Cologne Cologne Germany
References provided by Crossref.org
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