Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

"Form follows function": the developmental morphology of the cardiac atria

C. Neradilova, M. Gregorovicova, J. Kovanda, A. Kvasilova, V. Melenovsky, O. Nanka, D. Sedmera

. 2024 ; 73 (Suppl. 3) : S697-S714. [pub] 20241231

Status minimal Language English Country Czech Republic

Document type Journal Article, Review

Although the heart atria have a lesser functional importance than the ventricles, atria play an important role in the pathophysiology of heart failure and supraventricular arrhythmias, particularly atrial fibrillation. In addition, knowledge of atrial morphology recently became more relevant as cardiac electrophysiology and interventional procedures in the atria gained an increasingly significant role in the clinical management of patients with heart disease. The atrial chambers are thin-walled, and several vessels enter at the level of the atria. The left and right atrium have different structures and shape. In general, both atrial chambers have the venous part, the appendage, and the vestibule; different aspects of each part allow us to distinguish morphologically between the left and right atrium. The human atrial conduction system consists of the sinus node and the atrioventricular node with no histologically specialized conduction pathways in the atrial chamber and an interatrial connection. The data show that the propagation of the impulse depends mainly on the myocardial architecture in the atria and the orientation of the myocytes plays a significant role in conduction. To complete the picture, it is also important to know how the atria develop and what is the embryonic origin of its different structures, as this may play a role in the development of some pathological conditions such as atrial fibrillation or certain types of congenital heart defects. Functional impairment of the atria can in some situations severely compromise heart pumping function, and conversely, can support it if other areas are damaged, balancing the blood flow to the body for some time. Key words Morphology of atrial chambers, Pectinate muscles, Atrial function.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc25005540
003      
CZ-PrNML
005      
20250312151242.0
007      
ta
008      
250213s2024 xr f 000 0|eng||
009      
AR
024    7_
$a 10.33549/physiolres.935503 $2 doi
035    __
$a (PubMed)39808172
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Neradilova, C $u Children's Heart Center, Second Faculty of Medicine, Charles University and Motol University Hospital, Praha, Czech Republic. caroline.neradilova@fnmotol.cz
245    10
$a "Form follows function": the developmental morphology of the cardiac atria / $c C. Neradilova, M. Gregorovicova, J. Kovanda, A. Kvasilova, V. Melenovsky, O. Nanka, D. Sedmera
520    9_
$a Although the heart atria have a lesser functional importance than the ventricles, atria play an important role in the pathophysiology of heart failure and supraventricular arrhythmias, particularly atrial fibrillation. In addition, knowledge of atrial morphology recently became more relevant as cardiac electrophysiology and interventional procedures in the atria gained an increasingly significant role in the clinical management of patients with heart disease. The atrial chambers are thin-walled, and several vessels enter at the level of the atria. The left and right atrium have different structures and shape. In general, both atrial chambers have the venous part, the appendage, and the vestibule; different aspects of each part allow us to distinguish morphologically between the left and right atrium. The human atrial conduction system consists of the sinus node and the atrioventricular node with no histologically specialized conduction pathways in the atrial chamber and an interatrial connection. The data show that the propagation of the impulse depends mainly on the myocardial architecture in the atria and the orientation of the myocytes plays a significant role in conduction. To complete the picture, it is also important to know how the atria develop and what is the embryonic origin of its different structures, as this may play a role in the development of some pathological conditions such as atrial fibrillation or certain types of congenital heart defects. Functional impairment of the atria can in some situations severely compromise heart pumping function, and conversely, can support it if other areas are damaged, balancing the blood flow to the body for some time. Key words Morphology of atrial chambers, Pectinate muscles, Atrial function.
650    _2
$a lidé $7 D006801
650    12
$a srdeční síně $7 D006325
650    _2
$a zvířata $7 D000818
650    _2
$a převodní systém srdeční $x patofyziologie $7 D006329
650    _2
$a srdce - funkce síní $x fyziologie $7 D016275
650    _2
$a fibrilace síní $x patofyziologie $x patologie $7 D001281
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Gregorovicova, M
700    1_
$a Kovanda, J
700    1_
$a Kvasilova, A
700    1_
$a Melenovsky, V
700    1_
$a Nanka, O
700    1_
$a Sedmera, D
773    0_
$w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 73, Suppl. 3 (2024), s. S697-S714
856    41
$u https://pubmed.ncbi.nlm.nih.gov/39808172 $y Pubmed
910    __
$a ABA008 $b A 4120 $c 266 $y - $z 0
990    __
$a 20250213 $b ABA008
991    __
$a 20250312151249 $b ABA008
999    __
$a min $b bmc $g 2283575 $s 1242560
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 73 $c Suppl. 3 $d S697-S714 $e 20241231 $i 1802-9973 $m Physiological research $n Physiol Res $x MED00003824
LZP    __
$a Pubmed-20250213

Find record

Citation metrics

Loading data ...

Archiving options

Loading data ...