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Fluorometric and Colorimetric Biosensors for the Assay of Cholinesterase Inhibitors
M. Pohanka
Language English Country Switzerland
Document type Journal Article, Review
Grant support
DZRO-FVZ22-ZHN II
Ministry of Defence
NLK
Directory of Open Access Journals
from 2001
PubMed Central
from 2003
Europe PubMed Central
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ProQuest Central
from 2001-01-01
Open Access Digital Library
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Open Access Digital Library
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Health & Medicine (ProQuest)
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ROAD: Directory of Open Access Scholarly Resources
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PubMed
40363113
DOI
10.3390/s25092674
Knihovny.cz E-resources
- MeSH
- Acetylcholinesterase chemistry metabolism MeSH
- Biosensing Techniques * methods MeSH
- Butyrylcholinesterase chemistry metabolism MeSH
- Cholinesterase Inhibitors * analysis MeSH
- Fluorometry * methods MeSH
- Colorimetry * methods MeSH
- Metal Nanoparticles chemistry MeSH
- Humans MeSH
- Gold chemistry MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Cholinesterases, specifically acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), play critical roles in neurotransmission and are key targets for inhibitors with therapeutic and toxicological significance. This review focuses on the development and application of fluorometric and colorimetric biosensors for the detection of cholinesterase inhibitors. These biosensors take advantage of the unique properties of AChE and BChE to provide sensitive and selective detection methods essential for environmental monitoring, food safety, and clinical diagnostics. Recent advances in assay techniques, including the use of gold nanoparticles, pseudoperoxidase nanomaterials, and innovative enzyme-substrate interactions, are highlighted. This review also discusses challenges and future directions for optimizing these biosensors for practical applications, emphasizing their potential to enhance public health and safety.
References provided by Crossref.org
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