Determination of cholesterol turnover rate by a one-and two-pool kinetic analysis
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
144287
Knihovny.cz E-resources
- MeSH
- Arteriosclerosis blood MeSH
- Cholesterol, Dietary MeSH
- Cholesterol blood MeSH
- Diet, Atherogenic MeSH
- Rabbits MeSH
- Cricetinae MeSH
- Rats MeSH
- Guinea Pigs MeSH
- Mice MeSH
- Ascorbic Acid Deficiency blood MeSH
- Carbon Radioisotopes MeSH
- Animals MeSH
- Check Tag
- Rabbits MeSH
- Cricetinae MeSH
- Rats MeSH
- Guinea Pigs MeSH
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Cholesterol, Dietary MeSH
- Cholesterol MeSH
- Carbon Radioisotopes MeSH
The cholesterol turnover rate in rabbits with alimentary cholesterol atherosclerosis and in guinea-pigs with chronic vitamin C deficiency was studied by a one- and two-pool kinetic analysis. The one-pool analysis yielded exaggeraged values for the turnover rate, but the turnover rate differences between the control and experimental groups in the one- and the two-pool analysis were very similar. One-pool analysis can be used in initial studies to obtain preliminary data on the effect of nutritional, pharmacological and other factors on cholesterol turnover rate.
