High-level resistance to streptomycin in Escherichia coli with R1 plasmid and the analysis of genetic determinants
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
378779
DOI
10.1007/bf02927297
Knihovny.cz E-zdroje
- MeSH
- antibiotická rezistence MeSH
- Escherichia coli účinky léků enzymologie genetika MeSH
- mapování chromozomů * MeSH
- mutace MeSH
- R-plasmidy * MeSH
- streptomycin farmakologie MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- streptomycin MeSH
Some properties of streptomycin-resistant mutants of Escherichia coli were analyzed. In a R+ culture, the phenotype under study may be significantly selected at a frequency of 10(-5) on media with higher streptomycin level. The lrs mutation is present in the cells prior to the action of streptomycin and remains in the cells even after curing of the R1 plasmid. The mapping of the lrs gene by conjugation with a concomitant transfer of chromosome and the R1 plasmid in different Hfr strains of E. coli failed to establish the localization of this gene in the tested chromosome regions. The presence of a cryptic plasmid was detected in cells with the lrs mutation after curing of the R1 plasmid. This plasmid codes neither fertility functions nor chloramphenicol-acetyltransferase, streptomycin-adenyltransferase, or ampicillin-beta-lactamase.
Zobrazit více v PubMed
Folia Microbiol (Praha). 1973;18(3):263-5 PubMed
Ann N Y Acad Sci. 1971 Jun 11;182:226-33 PubMed
Folia Microbiol (Praha). 1977;22(3):198-205 PubMed
Folia Microbiol (Praha). 1978;23(4):278-85 PubMed
Infect Immun. 1970 Jan;1(1):109-19 PubMed
J Gen Microbiol. 1968 Jan;50(1):173-6 PubMed
Nature. 1967 May 27;214(5091):885-7 PubMed
Nature. 1949 Jul 23;164(4160):150 PubMed
Biochem J. 1962 May;83:236-40 PubMed
Bacteriol Rev. 1976 Mar;40(1):116-67 PubMed
Genet Res. 1970 Dec;16(3):359-65 PubMed
J Bacteriol. 1973 May;114(2):577-91 PubMed
Genetics. 1964 Feb;49:237-46 PubMed
Bacteriol Rev. 1972 Dec;36(4):525-57 PubMed
Biochem J. 1971 Jul;123(4):493-500 PubMed
J Biol Chem. 1951 Nov;193(1):265-75 PubMed
Folia Microbiol (Praha). 1973;18(3):257-62 PubMed
Antimicrob Agents Chemother. 1977 Aug;12(2):163-77 PubMed
J Gen Microbiol. 1973 Dec;79(2):257-64 PubMed