Steroid derivatives. LXXIX. Microbial 15 beta-hydroxylation of 17 alpha-acetoxy-16-methylene derivatives of the pregnane series by the action of Cunninghamella blakesleeana
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
947832
DOI
10.1007/bf02876982
Knihovny.cz E-zdroje
- MeSH
- chemické jevy MeSH
- chemie MeSH
- houby metabolismus MeSH
- hydroxylace MeSH
- Mucorales metabolismus MeSH
- pregnany metabolismus MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- pregnany MeSH
Hydroxylation of 17 alpha-acetoxy-6-chloro-16-methylene-4,6-pregnadiene-3,20-dione (Chlorosuperlutin, I) by Cunninghamella blakesleeana yielded a 15 beta-hydroxyderivative II. Analogous transformation of 17 alpha-acetoxy-16-methylene-4,6-pregnadiene-3,20-dione (Superlutin, IV) included a hydroxylation in position 15 beta and probably also in 11 beta with a concomitant reduction of the 6,7-double bond.
