Effect of crotonaldehyde on the metabolism of Candida utilis during the production of single cell protein from ethanol
Language English Country United States Media print
Document type Journal Article
PubMed
1033115
DOI
10.1007/bf02876935
Knihovny.cz E-resources
- MeSH
- Acetaldehyde metabolism MeSH
- Acetates biosynthesis metabolism MeSH
- Aerobiosis MeSH
- Acrolein analogs & derivatives pharmacology MeSH
- Aldehydes pharmacology MeSH
- Alcohols pharmacology MeSH
- Candida drug effects metabolism MeSH
- Nitrogen metabolism MeSH
- Ethanol metabolism MeSH
- Fungal Proteins biosynthesis MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Acetaldehyde MeSH
- Acetates MeSH
- Acrolein MeSH
- Aldehydes MeSH
- Alcohols MeSH
- Nitrogen MeSH
- Ethanol MeSH
- Fungal Proteins MeSH
The effect of 20 low-boiling compounds on the yeast Candida utilis 49 was assessed by a screening test on agar medium. The highest toxicity was exhibited by crotonaldehyde, allyl alcohol and acrolein. Oxidation and assimilation experiments in a slightly aerobic environment showed that an increase in the level of crotonaldehyde in the medium in the range of 10--20 mg 1-1 brings about a lowering of intensity of metabolic processes in Candida utilis, suppression of ethanol utilization and aerobic oxidation rate, a drop in biomass yield, prolongation of cultivation time, etc. The inhibitory effect of crotonaldehyde depends strongly on the manner of its dosage into the medium (single or continuous) and other cultivation conditions (intensity of medium aeration, physiological state of the culture, etc). Crotonaldehyde is lost from the medium partially by volatilization and partially due to chemical and biochemical transformation.
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