Structure-function subcompartments of the mammalian cell nucleus as revealed by the electron microscopic affinity cytochemistry
Language English Country Great Britain, England Media print
Document type Journal Article, Review
- MeSH
- Biomarkers MeSH
- Cell Nucleolus physiology ultrastructure MeSH
- Cell Nucleus physiology ultrastructure MeSH
- 3T3 Cells ultrastructure MeSH
- Chromatin ultrastructure MeSH
- DNA analysis MeSH
- Microscopy, Electron methods MeSH
- Transcription, Genetic * MeSH
- HeLa Cells ultrastructure MeSH
- Nuclear Proteins analysis MeSH
- Rats MeSH
- Humans MeSH
- Mice MeSH
- RNA Processing, Post-Transcriptional * MeSH
- Ribonucleoproteins analysis MeSH
- RNA analysis MeSH
- Structure-Activity Relationship MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Humans MeSH
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Biomarkers MeSH
- Chromatin MeSH
- DNA MeSH
- Nuclear Proteins MeSH
- Ribonucleoproteins MeSH
- RNA MeSH
This electron microscopy review documents the in situ cytochemical localization of important nuclear structures and relates this to the important nuclear functions of RNA transcription and processing. With the help of specific probes (antibodies, nucleic acid probes), a comprehensive picture of nuclear subcompartmentalization is beginning to emerge.
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