Non-quantal acetylcholine release after cholinesterase inhibition in vivo
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
1286102
Knihovny.cz E-resources
- MeSH
- Acetylcholine biosynthesis MeSH
- Armin pharmacology MeSH
- Cholinesterases physiology MeSH
- Electrophysiology MeSH
- Mice MeSH
- Motor Endplate drug effects MeSH
- Soman pharmacology MeSH
- Animals MeSH
- Check Tag
- Male MeSH
- Mice MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Acetylcholine MeSH
- Armin MeSH
- Cholinesterases MeSH
- Soman MeSH
After anticholinesterase treatment in vivo, depolarization of the postsynaptic muscle fibre membrane by about 4 mV develops due to non-quantally released acetylcholine from the motor nerve terminal. This conclusion was supported by experiments with the curarization of diaphragm slices from anticholinesterase treated mice during intracellular microelectrode recordings.
From Frog Muscle to Brain Neurons: Joys and Sorrows in Neuroscience
