A freeze-fracture study on the effect of neopybuthrin on the intestinal epithelial cells of Tilapia nilotica
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
1303110
Knihovny.cz E-zdroje
- MeSH
- epitel účinky léků ultrastruktura MeSH
- insekticidy farmakologie MeSH
- mrazové lámání MeSH
- pyrethriny farmakologie MeSH
- střevní sliznice účinky léků ultrastruktura MeSH
- Tilapia * MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- insekticidy MeSH
- neopybuthrin MeSH Prohlížeč
- pyrethriny MeSH
Freeze-fracture replicas of the plasma membrane and tight junctions (Tj) of intestinal epithelial cells were studied in Tilapia nilotica fish exposed to the pyrethroid insecticide, neopybuthrin. Exposing fishes to different repeated concentrations of 1/2 LC50 of neopybuthrin caused a significant decrease in the population density of IMPs in P- and E-faces. Tight junctions were also affected by neopybuthrin treatment. They appeared fragmented and discontinued, and their strands were fewer in number as compared with controls. Since the structure and number of Tj are major determinants of epithelial permeability, it is postulated that neopybuthrin treatment may affect the intestinal permeability of T. nilotica.
