Permeability factor, cytotoxicity and serotyping of Pseudomonas aeruginosa strains
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
1493904
DOI
10.1007/bf02815663
Knihovny.cz E-zdroje
- MeSH
- buněčná smrt MeSH
- kapilární permeabilita MeSH
- králíci MeSH
- lidé MeSH
- nádory mikrobiologie MeSH
- Pseudomonas aeruginosa klasifikace izolace a purifikace patogenita MeSH
- sérotypizace MeSH
- transplantace orgánů MeSH
- Vero buňky MeSH
- zevní ucho mikrobiologie MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
We analyzed in detail the permeability and cytotoxic activity as well as the serotypes of 127 Pseudomonas aeruginosa strains. Sixty-seven strains were isolated from immunocompromised patients (51 from patients with tumors and 16 from patients after transplantation) and 60 strains were isolated from patient's ears. Culture filtrates of strains isolated from patients after transplantation were responsible for the highest part of permeability reactions corresponding to an intermediate toxin production (68.8%) (categories 2 and 3) and culture filtrates of strains isolated from patients with tumors caused the highest percentage of permeability reactions corresponding to a strong toxin production. Culture filtrates of strains isolated from ears of patients were responsible for the highest percentage of negative permeability reactions (15%). With positive permeability reaction size (categories 2-6) increased also the percentage of cytotoxicity as well as the intensity of morphological changes on Vero cells after 1 and 2 d. We did not observe any relationship between a particular permeability reaction category and the most frequent serotypes (O4, O6) or nontypable strains of the tested groups.
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