Functional and metabolic changes of guinea pig peritoneal macrophages induced by bacterial vaccines
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
1505873
DOI
10.1007/bf02836621
Knihovny.cz E-zdroje
- MeSH
- bakteriální vakcíny imunologie MeSH
- makrofágy imunologie metabolismus MeSH
- morčata MeSH
- peritoneum MeSH
- Proteus mirabilis imunologie MeSH
- stafylokokové vakcíny imunologie MeSH
- Staphylococcus aureus imunologie MeSH
- zvířata MeSH
- Check Tag
- morčata MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- bakteriální vakcíny MeSH
- stafylokokové vakcíny MeSH
Phagocytic activity of peritoneal macrophages of guinea pigs injected subcutaneously with bacterial vaccines was found to be increased. The phagocytic index remained unchanged or was decreased. In addition, a decreased candidacidal activity was observed. Metabolic activation of macrophages, measured by the INT test, was inhibited in unstimulated cells while cells stimulated with zymosan or opsonized zymosan exhibited higher values of the INT test as compared with control animals. After injection of vaccines the number of peritoneal macrophages was increased, but the spleen mass decreased.
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