Comparative susceptibility studies of clinically isolated Pseudomonas aeruginosa, Escherichia coli and Klebsiella spp to cefoperazone and cefotaxime
Language English Country Czech Republic Media print
Document type Comparative Study, Journal Article
PubMed
2125616
Knihovny.cz E-resources
- MeSH
- Drug Resistance, Microbial MeSH
- Cefoperazone pharmacology MeSH
- Cefotaxime pharmacology MeSH
- Escherichia coli drug effects MeSH
- Klebsiella drug effects MeSH
- Microbial Sensitivity Tests MeSH
- Pseudomonas aeruginosa drug effects MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
- Names of Substances
- Cefoperazone MeSH
- Cefotaxime MeSH
The in-vitro activity of cefotaxime and cefoperazone were compared using clinically isolated Escherichia coli, Klebsiella spp and Pseudomonas aeruginosa. Cefotaxime was found on a weight to weight basis, to be much more active than cefoperazone. All the three species studied show the presence of cefoperazone-resistant population which were sensitive to cefotaxime. The possible mechanisms of resistance to these antibiotics were discussed.