Transmural non-homogeneity of calcium-induced heart injury
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
2144354
Knihovny.cz E-resources
- MeSH
- Adenosine Triphosphatases metabolism MeSH
- Phosphorylases metabolism MeSH
- Hydroxybutyrate Dehydrogenase metabolism MeSH
- Rats MeSH
- L-Lactate Dehydrogenase metabolism MeSH
- Myocardium enzymology MeSH
- Reperfusion Injury enzymology MeSH
- Succinate Dehydrogenase metabolism MeSH
- Calcium physiology MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Adenosine Triphosphatases MeSH
- Phosphorylases MeSH
- Hydroxybutyrate Dehydrogenase MeSH
- L-Lactate Dehydrogenase MeSH
- Succinate Dehydrogenase MeSH
- Calcium MeSH
The Ca paradox resulted in marked inhibition, up to disappearance, of histochemically studied enzyme activities (SDH, LDH, beta-HBDH, phosphorylase and ATPase) in the subepicardial layer of the myocardium. In the subendocardial region there was only a small decrease. These transmural differences correlated well with ultrastructural changes. It is assumed that the heterogeneity in transmural distribution of injury is the result of transmural differences in coronary flow.
Proteomic analysis of cardiac ventricles: baso-apical differences
