Single K+ currents during differentiation of embryonic muscle cells in vitro
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články
PubMed
2510830
DOI
10.1016/0005-2736(89)90284-8
PII: 0005-2736(89)90284-8
Knihovny.cz E-zdroje
- MeSH
- adenosintrifosfát farmakologie MeSH
- buněčná membrána fyziologie MeSH
- draslíkové kanály účinky léků fyziologie MeSH
- EGTA farmakologie MeSH
- elektrická vodivost MeSH
- elektrofyziologie přístrojové vybavení metody MeSH
- kultivované buňky MeSH
- kuřecí embryo MeSH
- membránové potenciály MeSH
- svaly fyziologie MeSH
- tetraethylamoniové sloučeniny farmakologie MeSH
- tetraethylamonium MeSH
- zvířata MeSH
- Check Tag
- kuřecí embryo MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- adenosintrifosfát MeSH
- draslíkové kanály MeSH
- EGTA MeSH
- tetraethylamoniové sloučeniny MeSH
- tetraethylamonium MeSH
After 3-7 days in culture, chicken myotubes possess five types of K+ channel: two high-conductance channels of 195 and 105 pS which are sensitive to tetraethylammonium (TEA), an ATP-sensitive channel of 64 pS and two low-conductance channels of 40 and 15 pS which are insensitive to TEA and ATP. The same population of channels is to be found in EGTA-treated muscle cells with blocked fusion and, with the exception of the ATP-sensitive channel, also in 1-day-old myoblasts. There are differences between myoblasts and myotubes in the percentage of incidence of individual channel types. High-conductance K+ channels are most frequently to be observed in myotubes, but they are rare in myoblasts and EGTA-treated cells where low-conductance K+ channels predominate.
Citace poskytuje Crossref.org
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