Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
2534480
Knihovny.cz E-zdroje
- MeSH
- antigeny CD45 MeSH
- antigeny povrchové imunologie MeSH
- CD antigeny imunologie MeSH
- diferenciační antigeny T-lymfocytů imunologie MeSH
- diferenciační antigeny imunologie MeSH
- elektroforéza v polyakrylamidovém gelu MeSH
- glykoproteiny imunologie MeSH
- hybridomy MeSH
- lidé MeSH
- molekulová hmotnost MeSH
- monoklonální protilátky biosyntéza imunologie MeSH
- myši inbrední BALB C MeSH
- myši MeSH
- receptory odpovědné za homing lymfocytů MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- myši MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antigeny CD45 MeSH
- antigeny povrchové MeSH
- CD antigeny MeSH
- diferenciační antigeny T-lymfocytů MeSH
- diferenciační antigeny MeSH
- glykoproteiny MeSH
- monoklonální protilátky MeSH
- receptory odpovědné za homing lymfocytů MeSH
Monoclonal antibodies against several human leucocyte cell surface antigens were prepared and characterized: (1) MEM-56, MEM-93, MEM-66, and MEM-104 against the CD45R antigen (220 kDa and 205 kDa mol. wt. forms of the leucocyte common antigen CD45 expressed on B-lymphocytes, myeloid cells and a subpopulation of T-lymphocytes); (2) MEM-98 and MEM-100 against the T-lymphocyte antigen CD6 (mol. wt. 100 kDa); (3) MEM-85 against the broadly expressed antigen CD44 (mol. wt. 85 kDa) which was recently shown by us to be identical with the lymphocyte homing receptor; (4) MEM-53 against a newly described broadly expressed antigen of 35-40 kDa mol. wt. and (5) MEM-102 against another newly described glycoprotein of 40 kDa mol. wt. anchored in membrane through a phosphatidylinositol moiety.
The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1
