Influence of thyroxine and propylthiouracil administration on the intake of maternal milk in sucklings of the laboratory rat
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
2931733
Knihovny.cz E-zdroje
- MeSH
- inbrední kmeny potkanů MeSH
- kojená zvířata fyziologie MeSH
- krysa rodu Rattus MeSH
- laktace MeSH
- mléko * MeSH
- oči - fyziologické jevy MeSH
- pití účinky léků MeSH
- propylthiouracil farmakologie MeSH
- radioizotopy stroncia metabolismus MeSH
- skupiny zvířecí populace fyziologie MeSH
- těhotenství MeSH
- tělesná hmotnost MeSH
- thyroxin farmakologie MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- propylthiouracil MeSH
- radioizotopy stroncia MeSH
- thyroxin MeSH
Young laboratory rats received a daily subcutaneous injection of thyroxine (T4) and propylthiouracil (PTU) in saline, from birth until the period of spontaneous weaning. The rate of growth and the time of eye opening as well as the spontaneous weaning was assessed. The intake of maternal milk was followed directly, i.e. by the transport of 85Sr in maternal milk from the maternal body to the sucklings. In the young treated with T4 the eyes opened earlier than in the young treated with PTU. The body mass differed in both groups between the 4th and 20th day of life (the T4 pups were heavier). The 85Sr transfer in maternal milk was higher in the PTU young from the 22nd day of life. The PTU sucklings weaned spontaneously one week later than those receiving T4. A hypothesis has been proposed on the primary significance of maturation of oral mechanisms of sucking for spontaneous weaning.
Effect of hypo- and hyperthyroid states on phospholipid composition in developing rat heart