Identification of transformation-specific proteins synthesized in cryptovirogenic mammalian cells
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
2991029
Knihovny.cz E-zdroje
- MeSH
- buněčné linie MeSH
- experimentální sarkom analýza mikrobiologie MeSH
- králíci MeSH
- křečci praví MeSH
- křeček rodu Mesocricetus MeSH
- kuřecí embryo MeSH
- nádorové proteiny imunologie izolace a purifikace MeSH
- onkogenní protein pp60(v-src) MeSH
- proteinkinasy izolace a purifikace MeSH
- protilátky nádorové imunologie MeSH
- virová transformace buněk * MeSH
- virové proteiny imunologie izolace a purifikace MeSH
- viry ptačího sarkomu MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- křečci praví MeSH
- kuřecí embryo MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- nádorové proteiny MeSH
- onkogenní protein pp60(v-src) MeSH
- proteinkinasy MeSH
- protilátky nádorové MeSH
- virové proteiny MeSH
The cryptovirogenic PR-RSH-19 (H-19) hamster cell line, derived originally from a tumour induced by the virus rescued from XC cells by transfection, was studied. The pp60v-src protein was detected by immunoprecipitation with sera from tumour-bearing rabbits (TBR sera) from lysates of H-19 cells. A closely related protein p60 was precipitated by antiserum obtained from hamsters with tumours induced by H-19 cells. The pp60v-src of H-19 cells possesses an associated kinase activity. These results are consistent with the notion that the detected pp60v-src protein is a product of the cryptic sequences in H-19 cells.
Tumor induction by the LTR, v-src, LTR DNA in four B (MHC) congenic lines of chickens
