Mobilization of intracellular calcium from the sarcoplasmic reticulum of B-lymphocytes using cyclic guanosine 3'5'-monophosphate (cGMP)
Journal of hygiene, epidemiology, microbiology, and immunology.
1986 ;
30 (3) :
295-9.
Language English Country Czech Republic Media print
Document type Journal Article
Persistent link
https://www.medvik.cz/link/pmid03021844
PubMed
3021844
Knihovny.cz E-resources
- MeSH
- B-Lymphocytes drug effects metabolism MeSH
- Phosphorylation MeSH
- Cyclic GMP pharmacology MeSH
- Microsomes drug effects enzymology metabolism MeSH
- Mice, Inbred C57BL MeSH
- Mice MeSH
- Protein Kinases metabolism MeSH
- Sarcoplasmic Reticulum drug effects metabolism MeSH
- Calcium metabolism MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Cyclic GMP MeSH
- Protein Kinases MeSH
- Calcium MeSH
Cyclic guanosine-3'5' monophosphate (cGMP) can mobilize intracellular calcium from the microsomal fraction of B-lymphocytes of the mouse spleen as a result of activation of cGMP-dependent microsomal proteinkinases. The existence of such a mechanism makes B-lymphocytes independent of extracellular calcium in response to agents whose effect on B-lymphocytes is mediated by calcium mechanisms.
