Steroid and steroid regulating hormones in human male castrates
Language English Country Germany Media print
Document type Comparative Study, Journal Article
PubMed
3150955
DOI
10.1055/s-0029-1210812
Knihovny.cz E-resources
- MeSH
- Androgens blood physiology MeSH
- Biomarkers MeSH
- Adult MeSH
- Follicle Stimulating Hormone blood MeSH
- Sex Hormone-Binding Globulin blood MeSH
- Gonadotropins blood physiology MeSH
- Hydrocortisone blood MeSH
- Adrenal Cortex physiology MeSH
- Middle Aged MeSH
- Humans MeSH
- Luteinizing Hormone blood MeSH
- Orchiectomy * MeSH
- Saliva metabolism MeSH
- Testosterone blood metabolism physiology MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
- Names of Substances
- Androgens MeSH
- Biomarkers MeSH
- Follicle Stimulating Hormone MeSH
- Sex Hormone-Binding Globulin MeSH
- Gonadotropins MeSH
- Hydrocortisone MeSH
- Luteinizing Hormone MeSH
- Testosterone MeSH
Testosterone, dihydrotestosterone, androstenedione, dehydroepiandrosterone and its sulphate, 11 beta-hydroxyandrostenedione, 17 alpha-hydroxyprogesterone, cortisol, LH, FSH and sex hormone binding globulin (SHBG) were determined in 16 otherwise healthy male castrates, orchidectomized for the forensic reasons. Their hormone levels were compared with those, obtained in normal males of the same age category. There were found in the castrates decreased levels of testosterone, dihydrotestosterone, dehydroepiandrosterone sulphate and androstenedione, unaltered concentrations of cortisol and dehydroepiandrosterone, whereas the levels of 11 beta-hydroxyandrostenedione, 17 alpha-hydroxyprogesterone, both gonadotrophins and SHBG were increased. The results point to the importance of the selective increase of the incretory activity of the adrenal cortex in situations, when the gonadal function is impaired or missing.
References provided by Crossref.org
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