Production of quinomycin A in Streptomyces lasaliensis
Language English Country United States Media print
Document type Journal Article
PubMed
3817656
DOI
10.1007/bf02877251
Knihovny.cz E-resources
- MeSH
- Quinoxalines biosynthesis MeSH
- Echinomycin biosynthesis isolation & purification MeSH
- Mutation MeSH
- Streptomyces cytology genetics metabolism MeSH
- Temperature MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Quinoxalines MeSH
- Echinomycin MeSH
In addition to lasalocid, an oligoether coccidiostatic compound, other compounds are synthesized by Streptomyces lasaliensis. Mutants producing either of two antibiotics, lasalocid A or quinomycin A (an antibiotic of quinoxaline character), were obtained by natural selection and by mutagenesis. Methods of isolation, purification and estimation of both compounds were established.
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