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Location of the gene responsible for Rous sarcoma regression in the B-F region of the B complex (MHC) of the chicken

. 1981 ; 27 (5) : 363-8.

Language English Country Czech Republic Media print

Document type Journal Article

We studied the fate of tumours induced by PR-RSV-C and B77-C in inbred chicken lines CB, CC and CB.R1. Rous sarcomas regressed in the CB and CB.R1 lines which are identical in the B-F region of the B complex. In contrast, progressive tumour growth was observed in the CC line which differed in the B-F region from the CB and CB.R1 lines and was identical in the B-G region with the CB.R1 line. These results suggest that the gene responsible for Rous sarcoma regression is located in the B-F region of the B complex.

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