Improving the production of monensin by Streptomyces cinnamonensis
Language English Country United States Media print
Document type Journal Article
PubMed
6370806
DOI
10.1007/bf02875906
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents biosynthesis MeSH
- Bacteriological Techniques MeSH
- Furans biosynthesis MeSH
- Monensin biosynthesis MeSH
- Gene Expression Regulation MeSH
- Streptococcus metabolism MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Furans MeSH
- Monensin MeSH
The production of monensin by Streptomyces cinnamonensis was increased by genetic improvement of the strain and by modification of cultivation conditions. The selection of a suitable strain and optimization of the fermentation process (temperature, aeration, addition of esters of oleic acid) resulted in a 30 fold increase of the monensin production.
See more in PubMed
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Antimicrob Agents Chemother (Bethesda). 1967;7:353-8 PubMed
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Propionate and the production of monensins in Streptomyces cinnamonensis
Effect of precursors on biosynthesis of monensins A and B
Estimation of lipase activity by the diffusion plate method
