Mutation modifying the serine pathway in methylotrophic bacteria
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
6792008
DOI
10.1007/bf02927420
Knihovny.cz E-zdroje
- MeSH
- Bacillus genetika metabolismus MeSH
- glycin farmakologie MeSH
- glycinhydroxymethyltransferasa metabolismus MeSH
- isocitrátlyasa metabolismus MeSH
- karbohydrátdehydrogenasy metabolismus MeSH
- kyseliny glycerové metabolismus MeSH
- methanol metabolismus MeSH
- Micrococcus genetika metabolismus MeSH
- mutace * MeSH
- serin metabolismus MeSH
- transaminasy metabolismus MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- Glycerate dehydrogenase MeSH Prohlížeč
- glycin MeSH
- glycine-oxaloacetate aminotransferase MeSH Prohlížeč
- glycinhydroxymethyltransferasa MeSH
- isocitrátlyasa MeSH
- karbohydrátdehydrogenasy MeSH
- kyseliny glycerové MeSH
- methanol MeSH
- serin MeSH
- transaminasy MeSH
Methylotrophic bacteria, Gram-positive, with the serine pathway, were shown to have their growth inhibited by 0.5% glycine. The effects of this amino acid on individual enzyme activities were studied in wild and mutant strains of Micrococcus varians and Bacillus licheniformis. The enzymes studied were glycerate dehydrogenase (EC 1.1.1.29), isocitrate lyase (EC 4.1.3.1), serine hydroxymethyltransferase (EC 2.1.2.1) and glycine--oxaloacetate aminotransferase (EC 2.6.1.35). The last-named enzyme was found to be inhibited, the kinetic constants having been determined for two strain types.
