Arabidopsis assay for mutagenicity

. 1994 Oct 16 ; 310 (2) : 249-56.

Jazyk angličtina Země Nizozemsko Médium print

Typ dokumentu časopisecké články, multicentrická studie

Perzistentní odkaz   https://www.medvik.cz/link/pmid07523895
Odkazy

PubMed 7523895
DOI 10.1016/0027-5107(94)90117-1
PII: 0027-5107(94)90117-1
Knihovny.cz E-zdroje

Four laboratories, two in the Czech Republic (Brno and Prague) and two in the CIS (Moscow and Duschanbe), participated in the International Programme on Chemical Safety's (IPCS) collaborative study to evaluate the utility of the most commonly used plant test systems, including the Arabidopsis thaliana assay, for assessing the mutagenic potential of environmental agents. Out of the five compounds evaluated in the Arabidopsis assay, three compounds, i.e., ethyl methanesulfonate, N-methyl-N-nitrosourea, and azidoglycerol, were reported to be mutagenic by all four participating laboratories. Sodium azide (NaN3) demonstrated a negative response in all four laboratories, whereas maleic hydrazide was reported to be weakly mutagenic by one laboratory and nonmutagenic by the other three laboratories.

Citace poskytuje Crossref.org

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