In vitro susceptibility to 9 antifungal agents of 14 strains of Zygomycetes isolated from clinical specimens
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články
PubMed
7739727
DOI
10.1007/bf01138473
Knihovny.cz E-zdroje
- MeSH
- allylamin analogy a deriváty farmakologie MeSH
- antifungální látky farmakologie MeSH
- azoly farmakologie MeSH
- flucytosin farmakologie MeSH
- lidé MeSH
- mikrobiální testy citlivosti MeSH
- Mucor účinky léků MeSH
- Mucorales účinky léků MeSH
- Rhizopus účinky léků MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- allylamin MeSH
- antifungální látky MeSH
- azoly MeSH
- flucytosin MeSH
- naftifine MeSH Prohlížeč
Fourteen clinical isolates of Zygomycetes were tested for their in vitro susceptibility to nine antifungal agents. Susceptibility assessment was performed using a microtiter broth dilution method. Synthetic broth with YNB and glucose was used for 5-fluorocytosine and BHI broth for all the other antimycotics. Amphotericin B exhibited the strongest activity against all isolates tested. MIC values of other two polyenes--nystatin and pimaricin--ranged within the susceptibility limits, with a little pronounced higher activity of pimaricin. The isolates of the genus Absidia and Syncephalastrum were well sensitive to all antimycotics with the exception of 5-fluorocytosine and naftifine. A very weak or zero growth inhibitory effect against all members of the genera Mucor and Rhizopus was found in azoles, 5-fluorocytosine and naftifine.
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Postgrad Med J. 1986 Nov;62(733):985-96 PubMed
Br J Ophthalmol. 1986 Aug;70(8):634-6 PubMed
Chemotherapy. 1989;35(4):267-72 PubMed
Antimicrob Agents Chemother. 1984 Jul;26(1):5-9 PubMed
Infection. 1985 May-Jun;13(3):134-6 PubMed
Postgrad Med. 1990 Jul;88(1):151-2, 155-61, 165-6 PubMed
Occurrence of itraconazole-tolerant micromycetes in the soil and food products
