Cyclosporins from Tolypocladium terricola
Language English Country England, Great Britain Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
7772305
DOI
10.1016/0031-9422(94)00711-2
PII: 0031-9422(94)00711-2
Knihovny.cz E-resources
- MeSH
- Cell Division drug effects MeSH
- Cyclosporins chemistry isolation & purification pharmacology MeSH
- Lymphocytes cytology drug effects MeSH
- Mitosporic Fungi chemistry MeSH
- Molecular Sequence Data MeSH
- Molecular Structure MeSH
- Mice, Inbred BALB C MeSH
- Mice MeSH
- Amino Acid Sequence MeSH
- Spectrum Analysis MeSH
- Animals MeSH
- Check Tag
- Mice MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Cyclosporins MeSH
New natural cyclosporins were isolated from the mycelium of surface cultivated fungus Tolypocladium terricola. The chemical structures of [Leu4] CS and [MeLeu1] CS = cyclosporin-J, were deduced from the NMR and mass spectral data. Biological activity of new cyclosporins is reported based on the proliferative mitogen stimulation test.
References provided by Crossref.org
Compounds isolated at the Institute of Microbiology in 1989-2001 and future trends